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韩国[具体内容]的鉴定及抗真菌药敏谱。 （原文“Identification and Antifungal Susceptibility Profiles of in Korea.”中“of”后面缺少具体内容，只能按现有结构翻译）

Identification and Antifungal Susceptibility Profiles of in Korea.

作者信息

Park Ji-Hyun, Oh Junsang, Sang Hyunkyu, Shrestha Bhushan, Lee Hyeyoung, Koo Jehyun, Cho Sung-Il, Choi Ji Seon, Lee Min-Ha, Kim Jayoung, Sung Gi-Ho

机构信息

Translational Research Division, Biomedical Institute of Mycological Resource, International St. Mary's Hospital and College of Medicine, Catholic Kwandong University, Incheon, Korea.

Department of Laboratory Medicine, International St. Mary's Hospital and College of Medicine, Catholic Kwandong University, Incheon, Korea.

出版信息

Mycobiology. 2019 Sep 3;47(4):449-456. doi: 10.1080/12298093.2019.1651592. eCollection 2019.

DOI:10.1080/12298093.2019.1651592
PMID:32010466
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6968713/
Abstract

Invasive fungal infections caused by have recently increased. However, biochemical kits such as API 20 C AUX and Vitek-2C have misidentified this species as other spp. such as or due to no information of in yeast database. During our 2016-2017 surveys, eleven isolates of were obtained in International St. Mary's Hospital in Korea. Here, we describe its morphological and molecular characteristics and tested its antifungal susceptibility against nine antifungal agents. The sequences of the ITS region and the D1/D2 region of LSU revealed 100% identity with the sequences of . In comparison with the results from MALDI-TOF mass spectrometry, we found that can be distinguished from other species. In antifungal susceptibility test, voriconazole and echinocandins exhibited good antifungal activities against the majority of isolates despite the absence of standard criteria.

摘要

由[具体真菌名称未给出]引起的侵袭性真菌感染近来有所增加。然而，诸如API 20 C AUX和Vitek - 2C等生化鉴定试剂盒由于酵母数据库中没有[该真菌名称]的信息，将该菌种误鉴定为其他菌种，如[其他菌种名称1]或[其他菌种名称2]。在我们2016 - 2017年的调查中，在韩国国际圣玛丽医院获得了11株[该真菌名称]分离株。在此，我们描述了其形态和分子特征，并测试了其对9种抗真菌药物的抗真菌敏感性。ITS区域和LSU的D1/D2区域序列与[相关参考真菌名称]的序列显示出100%的同一性。与基质辅助激光解吸电离飞行时间质谱（MALDI - TOF MS）的结果相比，我们发现[该真菌名称]可以与其他菌种区分开来。在抗真菌药敏试验中，尽管没有标准标准，但伏立康唑和棘白菌素对大多数[该真菌名称]分离株表现出良好的抗真菌活性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c170/6968713/5ffe14876a3b/TMYB_A_1651592_F0003_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c170/6968713/4c7dbaa5e8b0/TMYB_A_1651592_F0001_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c170/6968713/b6c4250a2ec4/TMYB_A_1651592_F0002_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c170/6968713/5ffe14876a3b/TMYB_A_1651592_F0003_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c170/6968713/4c7dbaa5e8b0/TMYB_A_1651592_F0001_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c170/6968713/b6c4250a2ec4/TMYB_A_1651592_F0002_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c170/6968713/5ffe14876a3b/TMYB_A_1651592_F0003_C.jpg

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