Wang Ruihang, Zhao Jing, Sun Ye, Yu Hui, Zhou Ning, Zhang Hongxia, Jia Dagong
College of Precision Instrument and Opto-electronics Engineering, Tianjin University, Tianjin 300072, China.
Department of Mechanical Engineering-Engineering Mechanics and the Department of Biomedical Engineering, Michigan Technological University, Houghton, MI 49931, USA.
Biomed Opt Express. 2019 Dec 18;11(1):316-329. doi: 10.1364/BOE.376782. eCollection 2020 Jan 1.
Continuous respiratory monitoring is extensively important in clinical applications. To effectively assess respiration rate (RR), tidal volume (TV), and minute ventilation (MV), we propose and experimentally demonstrate a respiration monitoring system using an in-line few-mode fiber Mach-Zehnder interferometer (FMF-MZI), which is the first to introduce in-line MZI into an optimal wearable design for respiration rate and volume monitoring. The optimal linear region of the proposed sensor is analyzed and positioned by a flexible arch structure with curvature sensitivity up to 8.53 dB/m. Respiration monitoring results are in good agreement with a standard spirometer among different individuals. The difference in TV estimation is ± 0.2 L, and the overall error of MV estimation is less than 5%.
连续呼吸监测在临床应用中极为重要。为了有效评估呼吸频率（RR）、潮气量（TV）和分钟通气量（MV），我们提出并通过实验证明了一种使用在线少模光纤马赫-曾德尔干涉仪（FMF-MZI）的呼吸监测系统，这是首次将在线MZI引入用于呼吸频率和容量监测的最佳可穿戴设计中。所提出的传感器的最佳线性区域通过具有高达8.53 dB/m曲率灵敏度的柔性拱形结构进行分析和定位。不同个体之间的呼吸监测结果与标准肺活量计的结果高度一致。潮气量估计的差异为±0.2 L，分钟通气量估计的总体误差小于5%。
