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卵巢甲状腺肿中的恶性甲状腺型乳头状肿瘤:一例报告

Malignant Thyroid-type Papillary Neoplasm in Struma Ovarii: A Case Report.

作者信息

Hassan Syed Adeel, Akhtar Ali, Falah Noor Ul, Sheikh Fahad N

机构信息

Internal Medicine, Dow University of Health Sciences, Karachi, PAK.

Internal Medicine, Shaukat Khanum Memorial Cancer Hospital and Research Centre, Lahore, PAK.

出版信息

Cureus. 2019 Dec 23;11(12):e6450. doi: 10.7759/cureus.6450.

Abstract

Papillary thyroid carcinoma (PTC) arising in a coexistent struma ovarii (SO) is a rare malignancy. It manifests with abdominal symptoms such as palpable mass, pain, distension, and possibly ascites. It is usually diagnosed postoperatively, and its histopathological diagnostic criteria remain identical to that of papillary carcinoma of the thyroid gland. Due to the relative rarity of the disease, definitive guidelines for its overall management are still undefined. We present a case of a 51-year old female with suspicion of a left ovarian tumor due to her presenting symptoms: raised serum CA-125 levels and abnormal abdominopelvic CT scan findings. She underwent complete surgical debulking of the mass (total abdominal hysterectomy (TAH), bilateral salpingo-oophorectomy (BSO), omentectomy, appendectomy, and pelvic lymphadenectomy). The mass was postoperatively diagnosed by histopathology as PTC in SO (stage IA). Furthermore, our patient did not receive any adjuvant treatment. The patient has been disease-free for 24 months post-surgery and is scheduled for regular biannual follow-ups.

摘要

合并存在卵巢甲状腺肿(SO)的甲状腺乳头状癌(PTC)是一种罕见的恶性肿瘤。其表现为腹部症状,如可触及肿块、疼痛、腹胀,可能还有腹水。通常在术后诊断,其组织病理学诊断标准与甲状腺乳头状癌相同。由于该疾病相对罕见,其整体管理的明确指南仍未确定。我们报告一例51岁女性病例,因其出现血清CA-125水平升高和腹部盆腔CT扫描结果异常等症状而怀疑患有左侧卵巢肿瘤。她接受了肿块的完全手术切除(全腹子宫切除术(TAH)、双侧输卵管卵巢切除术(BSO)、大网膜切除术、阑尾切除术和盆腔淋巴结清扫术)。术后经组织病理学诊断该肿块为卵巢甲状腺肿中的PTC(IA期)。此外,我们的患者未接受任何辅助治疗。患者术后已无病生存24个月,计划每半年进行定期随访。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7aa6/6975244/2323a3c5628b/cureus-0011-00000006450-i01.jpg

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