Ahmed Amjad M, Ahmed Dalia, Alfaris Mousa, Holmes Amanda, Aljizeeri Ahmed, Al-Mallah Mouaz H
King Abdulaziz Cardiac Center, King Abdulaziz Medical City for National Guard - Riyadh, Saudi Arabia.
Houston Methodist DeBakey Heart & Vascular Center, Houston, Texas, USA.
Qatar Med J. 2020 Jan 23;2019(3):20. doi: 10.5339/qmj.2019.20. eCollection 2019.
Frailty is a state of vulnerability and a decreased physiological response to stressors. As the population ages, the prevalence of frailty is expected to increase. Thus, identifying tools and resources that efficiently predict frailty among the Saudi population is important. We aimed to describe the prevalence and predictors of frailty among Saudi patients referred for cardiac stress testing with nuclear imaging. We included 876 patients (mean age 60.3 ± 11 years, women 48%) who underwent clinically indicated cardiac nuclear stress testing between January and October 2016. Fried Clinical Frailty Scale was used to assess frailty. Patients were considered frail if they had a score of four or higher. Multivariate adjusted logistic regression models were used to determine the independent predictors of elderly frail patients. In this cohort, the median age of the included patients was 61 years, and the prevalence of frailty was 40%. The frail patients were older, more frequently women, and had a higher body mass index. Additionally, frailty was associated with a higher prevalence of cardiovascular risk factors: hypertension (85% vs. 70%) and diabetes (75% vs. 60%). In a fully adjusted logistic regression model, women, hypertension, and obesity (BMI ≥ 30 kg/m) were independent predictors of elderly frail patients. With the aging of the Saudi population, frailty prevalence is expected to increase. Elderly, obesity, hypertension, and female gender are risk factors of frailty. Interventions to reduce frailty should be focused on this high-risk population.
衰弱是一种脆弱状态，是对压力源的生理反应降低。随着人口老龄化，衰弱的患病率预计会上升。因此，识别能够有效预测沙特人群中衰弱情况的工具和资源很重要。我们旨在描述接受核成像心脏负荷试验的沙特患者中衰弱的患病率及预测因素。我们纳入了876例患者（平均年龄60.3±11岁，女性占48%），这些患者在2016年1月至10月期间接受了临床指征的心脏核素负荷试验。采用弗里德临床衰弱量表评估衰弱情况。如果患者得分达到4分或更高，则被视为衰弱。使用多变量调整逻辑回归模型来确定老年衰弱患者的独立预测因素。在这个队列中，纳入患者的年龄中位数为61岁，衰弱患病率为40%。衰弱患者年龄更大，女性更为常见，且体重指数更高。此外，衰弱与心血管危险因素的患病率较高有关：高血压（85%对70%）和糖尿病（75%对60%）。在一个完全调整的逻辑回归模型中，女性、高血压和肥胖（体重指数≥30kg/m²）是老年衰弱患者的独立预测因素。随着沙特人口老龄化，衰弱患病率预计会上升。老年人、肥胖、高血压和女性性别是衰弱的危险因素。减少衰弱的干预措施应聚焦于这一高危人群。
