Gerçik Önay, Solmaz Dilek, Karasu Şebnem, Ekinci Neşe, Akar Servet
Department of Rheumatology, Katip Çelebi University Atatürk Training and Research Hospital, İzmir, Turkey.
Department of Radiology, Katip Çelebi University Atatürk Training and Research Hospital, İzmir, Turkey.
Arch Rheumatol. 2019 Apr 22;34(4):447-450. doi: 10.5606/ArchRheumatol.2019.7306. eCollection 2019 Dec.
Cytomegalovirus infection, which can occur as a result of reactivation due to immunosuppressive treatment in patients with granulomatosis with polyangiitis, is a serious condition that should be kept in mind because of its fatal course. In this article, we report a 49-year-old male patient with a diagnosis of granulomatosis with polyangiitis who developed a life-threatening colonic ulcer due to cytomegalovirus colitis and a shrunken spleen with irregular contours that was detected on abdominal computed tomography. This is a rare case of cytomegalovirus disease in a patient with granulomatosis with polyangiitis and splenic necrosis.
巨细胞病毒感染可因免疫抑制治疗导致血管炎合并肉芽肿病患者病毒重新激活而发生,这是一种严重情况,因其致命病程而应予以关注。在本文中,我们报告了一名49岁男性患者,诊断为血管炎合并肉芽肿病,因巨细胞病毒性结肠炎出现危及生命的结肠溃疡,腹部计算机断层扫描检测到脾脏缩小且轮廓不规则。这是血管炎合并肉芽肿病患者发生巨细胞病毒病及脾坏死的罕见病例。