Department of Otolaryngology, Head and Neck Surgery, Kaplan Medical Center, Rehovot, Israel.
Hadassah Medical School, Hebrew University, Jerusalem, Israel.
Laryngoscope. 2021 Jan;131(1):10-16. doi: 10.1002/lary.28528. Epub 2020 Feb 3.
Endoscopic dacryocystorhinostomy (eDCR) is the preferred approach for nasolacrimal duct obstruction, yet quality data on long-term outcomes is lacking.
A retrospective study in a single, academic institution.
To assess the 5- and 10-year success rates of eDCR, and its associated risks.
All eDCRs conducted at Kaplan Medical Center between the years 2002-2017 were included. For long-term follow-up analysis, two subgroups with a minimum of documented 5- and 10-year follow-up after surgery were defined. Surgical success was defined by both anatomical (observed patent lacrimal flow) and functional (symptomatic relief) success. Data was collected from the hospital's electronic medical records and was completed by phone interviews. Pre-, intra-, and postoperative variables were collected and stratified by multivariate analysis.
After exclusions, 321, 168, and 65 patients were included for immediate, 5- and 10-year outcome analysis, respectively. Overall success rates were 92.5%, 86.3%, and 80%, respectively. The anatomical success rates were 93.8%, 89.9%, and 86.1%, respectively. Multivariate analysis revealed that older age (P < .001, P = .001) previous smoking (P = .043, P = .037), and postoperative complains of epiphora (even when a successful irrigation was observed, P < .001, P = .01) were all associated with eDCR failure 5 and 10 years following surgery. Male gender was also associated with eDCR failure (5 years, P = .045; 10 years, P = .063).
Despite decreased rates over time, eDCR is beneficial for the majority of patients also at 10 years following surgery. Older age, smoking, postoperative epiphora, and male gender are related to long-term failure and should be discussed with the patients before surgery.
3b Laryngoscope, 131:10-16, 2021.
内镜下鼻内泪囊鼻腔吻合术(eDCR)是治疗鼻泪管阻塞的首选方法,但缺乏长期疗效的确切数据。
单中心回顾性研究。
评估 eDCR 的 5 年和 10 年成功率及其相关风险。
纳入 2002 年至 2017 年期间在卡普兰医疗中心进行的所有 eDCR。为了进行长期随访分析,定义了两个至少有 5 年和 10 年手术随访记录的亚组。手术成功定义为解剖学(观察到通畅的泪液流)和功能(症状缓解)成功。数据从医院的电子病历中收集,并通过电话访谈完成。收集术前、术中、术后变量,并进行多变量分析分层。
排除后,分别有 321、168 和 65 例患者纳入即时、5 年和 10 年结果分析,总体成功率分别为 92.5%、86.3%和 80%。解剖成功率分别为 93.8%、89.9%和 86.1%。多变量分析显示,年龄较大(P<0.001,P=0.001)、既往吸烟史(P=0.043,P=0.037)和术后溢泪症状(即使冲洗通畅,P<0.001,P=0.01)与术后 5 年和 10 年 eDCR 失败相关。男性性别也与 eDCR 失败相关(5 年,P=0.045;10 年,P=0.063)。
尽管随着时间的推移,eDCR 的成功率有所下降,但对于大多数患者来说,手术后 10 年仍有益。年龄较大、吸烟史、术后溢泪和男性性别与长期失败相关,应在手术前与患者讨论。
3b 级 喉镜,131:10-16,2021 年。