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老年和超高龄人群的内镜下泪囊鼻腔吻合术-病例对照研究。

Endoscopic dacryocystorhinostomy among the old and oldest-old populations - A case control study.

机构信息

Hadassah Medical School, Hebrew University, Jerusalem, Israel.

Hadassah Medical School, Hebrew University, Jerusalem, Israel; Department of Otolaryngology, Head and Neck Surgery, Kaplan Medical Center, Rehovot, Israel.

出版信息

Auris Nasus Larynx. 2021 Oct;48(5):898-904. doi: 10.1016/j.anl.2021.02.010. Epub 2021 Mar 18.

Abstract

OBJECTIVE

Despite increased risks of nasolacrimal duct obstruction (NLDO) with age, and the continuous growth of the old population proportion, data on endoscopic dacryocystorhinostomy (eDCR) among the old is lacking. This study aims to evaluate long-term eDCR efficacy and safety in the old and oldest-old population.

METHODS

A retrospective case-control study of patients aged 80 ≤ (oldest-old) and 65-79 (old) compared with younger controls who underwent eDCR, between 2002 and 2017. Pre-, intra- and postoperative factors were collected using an integrated hospital-community system. Success rates were analyzed and measured at the first visit following surgery (immediate success), and after five years. Demographics, comorbidities, complications rates, and outcomes were compared between the groups.

RESULTS

The study groups included 52 oldest-old patients (mean age 83.4 ± 3.6), 127 old patients (72.3 ± 4.14) and 142 control patients (57.8 ± 18.0). The immediate and success rates were 94.2%, 93.7% and 90.8% and five-year success rates were 80.0%, 76.6% and 80% among oldest-old, old and controls, respectively. No significant differences in success rates were found, even despite higher comorbidity rates among the study's group (96 and 92.8% vs. 63.2%, among oldest-old, old and controls respectively, p <0.001). Intra- and postoperative complications rates were low in all groups.

CONCLUSIONS

Among older population, including oldest-old and old, eDCR safety and long-term outcomes are comparable with younger patients, suggesting that eDCR should be offered to NLDO patients, regardless of age.

摘要

目的

尽管年龄增长会增加鼻泪管阻塞(NLDO)的风险,且老年人口比例持续增长,但针对老年人群行内镜下鼻内泪囊鼻腔吻合术(eDCR)的数据仍较为缺乏。本研究旨在评估高龄及超高龄人群行 eDCR 的长期疗效和安全性。

方法

回顾性病例对照研究,纳入 2002 年至 2017 年间在我院行 eDCR 的年龄≥80 岁(超高龄)和 65-79 岁(高龄)患者,并与较年轻的对照组进行比较。使用综合医院-社区系统收集术前、术中和术后的相关因素。术后即刻(即刻成功)和五年后对成功率进行分析和测量。比较各组的人口统计学、合并症、并发症发生率和结局。

结果

研究组包括 52 例超高龄患者(平均年龄 83.4±3.6 岁)、127 例高龄患者(72.3±4.14 岁)和 142 例对照组患者(57.8±18.0 岁)。超高龄、高龄和对照组的即刻成功率分别为 94.2%、93.7%和 90.8%,五年成功率分别为 80.0%、76.6%和 80.0%。尽管研究组的合并症发生率较高(超高龄、高龄和对照组分别为 96%和 92.8% vs. 63.2%,p<0.001),但三组间的成功率差异无统计学意义。所有组的术中及术后并发症发生率均较低。

结论

在老年人群中,包括超高龄和高龄患者,eDCR 的安全性和长期疗效与年轻患者相当,这提示无论年龄大小,都应向 NLDO 患者提供 eDCR 治疗。

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