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一名感染性心内膜炎患者由长奈瑟菌引起的菌血症:病例报告及文献复习

Bacteremia Caused by Neisseria elongata in an Infective Endocarditis Patient: Case Report and Review of Literature.

作者信息

Chen Yili, Liu Xiaochen, Ai Lu, Guo Penghao, Huang Han

出版信息

Clin Lab. 2020 Jan 1;66(1). doi: 10.7754/Clin.Lab.2019.190333.

Abstract

BACKGROUND

Neisseria elongata (N. elongate) is a strictly aerobic and gram-negative rod bacterium which is a constituent of the commensal bacterial flora in the pharynx. Infection caused by Neisseria elongata is rarely reported. Here we describe a case of endocarditis in a patient after aortic mechanical valve replacement caused by N. elon-gate in China.

METHOD

A 30-year-old man suffered infective endocarditis after aortic mechanical valve replacement. Blood cultures were positive and the organism was identified as Neisseria elongata by MALDI-TOF MS as well as the 16S rRNA sequencing.

RESULT

The patient was treated with ofloxacin and meropenem. He was successfully treated with the 6-week course of antibiotic therapy.

CONCLUSIONS

N. elongate endocarditis is rarely reported. Our report expands the range of infection caused by N. elongate.

摘要

背景

长奈瑟菌是一种严格需氧的革兰氏阴性杆菌,是咽部共生菌群的组成部分。由长奈瑟菌引起的感染鲜有报道。在此,我们描述了中国一名主动脉机械瓣膜置换术后患者发生的由长奈瑟菌引起的心内膜炎病例。

方法

一名30岁男性在主动脉机械瓣膜置换术后发生感染性心内膜炎。血培养呈阳性,通过基质辅助激光解吸电离飞行时间质谱(MALDI-TOF MS)以及16S rRNA测序鉴定该病原体为长奈瑟菌。

结果

患者接受了氧氟沙星和美罗培南治疗。经过为期6周的抗生素治疗,他成功康复。

结论

长奈瑟菌心内膜炎鲜有报道。我们的报告扩展了由长奈瑟菌引起的感染范围。

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