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Neurotracker 能否用作儿童轻度创伤性脑损伤后康复的临床标志物?一项探索性研究。

Could Neurotracker be used as a clinical marker of recovery following pediatric mild traumatic brain injury? An exploratory study.

机构信息

Département des Sciences de L'activité Physique, Université du Québec à Trois-Rivières, Québec, Canada.

School of Physical and Occupational Therapy, Mcgill University, Québec, Canada.

出版信息

Brain Inj. 2020 Feb 23;34(3):385-389. doi: 10.1080/02699052.2020.1723699. Epub 2020 Feb 4.

DOI:10.1080/02699052.2020.1723699
PMID:32013583
Abstract

PRIMARY OBJECTIVE

This study aimed to explore the potential for the Neurotracker, a perceptual-cognitive, multiple-object tracking test, and train paradigm, as a marker of functional recovery after mild traumatic brain injury (mTBI). It is hypothesized that Neurotracker could serve as a proxy for assessing cerebral functioning.

RESEARCH DESIGN

A comparative, 6 time points, longitudinal study design was used to compare Neurotracker performance between children and adolescents who were clinically recovered from mTBI and healthy controls.

METHODS AND PROCEDURES

Clinical measures were collected at the initial and final visits. Neurotracker trainings were performed at each of the 6 visits. Speed thresholds (Neurotracker performance) were recorded at each visit.

MAIN OUTCOMES AND RESULTS

A two-way repeated measures ANOVA suggested no differences between the groups but a significant time effect was apparent.

CONCLUSIONS

Clinically recovered children and adolescents exhibit similar training abilities to control subjects on this task. These results support further investigations using Neurotracker as a marker of recovery following mTBI.

摘要

主要目标

本研究旨在探索 Neurotracker(一种感知认知、多目标跟踪测试和训练范式)作为轻度创伤性脑损伤 (mTBI) 后功能恢复的标志物的潜力。假设 Neurotracker 可以作为评估大脑功能的替代指标。

研究设计

采用比较性、6 个时间点、纵向研究设计,比较临床康复的 mTBI 儿童和青少年与健康对照组在 Neurotracker 表现上的差异。

方法和程序

在初始和最后一次就诊时收集临床测量值。在 6 次就诊中的每一次都进行 Neurotracker 训练。在每次就诊时记录速度阈值(Neurotracker 表现)。

主要结果和结论

双因素重复测量方差分析表明组间无差异,但时间效应明显。

结论

在这项任务中,临床康复的儿童和青少年与对照组具有相似的训练能力。这些结果支持进一步使用 Neurotracker 作为 mTBI 后恢复的标志物进行研究。

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