Snowden Taylor, Ohlhauser Lisa, Morrison Jamie, Faubert Jocelyn, Gawryluk Jodie, Christie Brian R
Division of Medical Sciences, University of Victoria, Victoria, British Columbia, Canada.
Institute of Aging and Lifelong Health, University of Victoria, Victoria, British Columbia, Canada.
Neurotrauma Rep. 2023 Aug 14;4(1):522-532. doi: 10.1089/neur.2023.0009. eCollection 2023.
Many traumatic brain injury (TBI) survivors face scheduling and transportation challenges when seeking therapeutic interventions. The COVID-19 pandemic created a shift in the use of at-home spaces for work, play, and research, inspiring the development of online therapeutic options. In the current study, we determined the feasibility of an at-home cognitive training tool (NeuroTrackerX) that uses anaglyph three-dimensional (3D) glasses and three-dimensional multiple object tracking (3D-MOT) software. We recruited 20 adults (10 female; mean age = 68.3 years, standard deviation [SD] = 6.75) as the at-home training group. We assessed cognitive health status for participants using a self-report questionnaire and the Mini-Mental State Examination (MMSE), and all participants were deemed cognitively healthy (MMSE >26). At-home participants loaned the necessary equipment (e.g., 3D glasses, computer equipment) from the research facilities and engaged in 10 training sessions over 5 weeks (two times per week). Participant recruitment, retention, adherence, and experience were used as markers of feasibility. For program validation, 20 participants (10 female; mean age = 63.39 years, SD = 12.22), who had previously completed at least eight sessions of the in-lab 3D-MOT program, were randomly selected as the control group. We assessed individual session scores, overall improvement, and learning rates between groups. Program feasibility is supported by high recruitment and retention, 90% participant adherence, and participants' ease of use of the program. Validation of the program is supported. Groups showed no differences in session scores ( > 0.05) and percentage improvement ( > 0.05) despite the differences in screen size and 3D technology. Participants in both groups showed significant improvements in task performance across the training sessions ( < 0.001). NeuroTrackerX provides a promising at-home option for cognitive training in cognitively healthy adults and may be a promising avenue as an at-home therapeutic for TBI survivors. This abstract was previously published on clinicaltrials.gov and can be found at: https://www.clinicaltrials.gov/ct2/show/NCT05278273.
许多创伤性脑损伤（TBI）幸存者在寻求治疗干预时面临时间安排和交通方面的挑战。新冠疫情促使人们将家庭空间用于工作、娱乐和研究，从而推动了在线治疗方案的发展。在本研究中，我们确定了一种使用立体三维（3D）眼镜和三维多目标追踪（3D-MOT）软件的家庭认知训练工具（NeuroTrackerX）的可行性。我们招募了20名成年人（10名女性；平均年龄 = 68.3岁，标准差[SD] = 6.75）作为家庭训练组。我们使用自我报告问卷和简易精神状态检查表（MMSE）对参与者的认知健康状况进行评估，所有参与者均被判定认知健康（MMSE>26）。在家参与训练的参与者从研究机构借取必要的设备（如3D眼镜、计算机设备），并在5周内进行10次训练课程（每周两次）。参与者的招募、留存、依从性和体验被用作可行性的指标。为了进行项目验证，随机选择20名参与者（10名女性；平均年龄 = 63.39岁，SD = 12.22）作为对照组，这些参与者此前已完成至少八次实验室3D-MOT项目课程。我们评估了两组之间的单次训练成绩、总体改善情况和学习率。高招募率和留存率、90%的参与者依从性以及参与者对该项目的易用性支持了项目的可行性。该项目的验证也得到了支持。尽管屏幕尺寸和3D技术存在差异，但两组在单次训练成绩（>0.05）和改善百分比（>0.05）方面没有差异。两组参与者在整个训练课程中的任务表现均有显著改善（<0.001）。NeuroTrackerX为认知健康的成年人提供了一种有前景的家庭认知训练选择，并且可能成为TBI幸存者的一种有前景的家庭治疗途径。本摘要先前已发表在clinicaltrials.gov上，可在以下网址查阅：https://www.clinicaltrials.gov/ct2/show/NCT05278273。
