"I. Cantacuzino" Clinical Hospital, Bucharest, Romania.
"Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
Anticancer Res. 2020 Feb;40(2):1049-1053. doi: 10.21873/anticanres.14041.
BACKGROUND/AIM: Retroperitoneal sarcomas represent very aggressive malignancies with high capacity of invading the surrounding vital structures.
We present the case of a 46-year-old patient who had been initially diagnosed with a large retroperitoneal mass 18 months ago. At that moment the mass was resected en bloc with the inferior cava vein, which was reconstructed using a cadaveric graft, the histopathological studies demonstrating the presence of a leiomyosarcoma. One year later she was diagnosed with recurrent disease invading the abdominal aorta and a liver metastasis. This time the recurrence was resected en bloc with the abdominal aorta, which was reconstructed by placing a cadaveric graft; atypical liver resection was also performed. The postoperative course was uneventful.
Extended vascular resections and cadaveric graft reconstructions might be needed in order to achieve a good local control of the disease in patients with retroperitoneal sarcomas.
背景/目的：腹膜后肉瘤是一种侵袭性很强的恶性肿瘤，有很强的侵犯周围重要结构的能力。
我们报告了一例 46 岁患者的病例，她在 18 个月前最初被诊断为巨大的腹膜后肿块。当时整块切除了肿块和下腔静脉，使用尸体移植物重建了下腔静脉，组织病理学研究显示存在平滑肌肉瘤。一年后，她被诊断为复发疾病侵犯了腹主动脉和肝脏转移。这次复发是整块切除了腹主动脉，并用尸体移植物进行了重建；还进行了非典型性肝切除术。术后过程顺利。
为了实现腹膜后肉瘤患者的良好局部疾病控制，可能需要进行广泛的血管切除和尸体移植物重建。
