University of Colorado Anschutz Medical Campus, Department of Immunology and Microbiology, Aurora, Colorado, USA
J Bacteriol. 2020 Mar 26;202(8). doi: 10.1128/JB.00040-20.
In this issue of , Price et al. show that the -produced exopolysaccharide alginate protects by dampening the expression of virulence products that usually inhibit respiration and cell membrane integrity when the two organisms compete in other environments (C. E. Price, D. G. Brown, D. H. Limoli, V. V. Phelan, and G. A. O'Toole, J Bacteriol 202:e00559-19, 2020, https://doi.org/10.1128/jb.00559-19). This is the first report that exogenously added alginate affects competition and provides a partial explanation for and coinfections in cystic fibrosis.
本期《细菌学杂志》中，Price 等人表明，-产生的胞外多糖海藻酸盐通过抑制两种生物在其他环境中竞争时通常抑制呼吸和细胞膜完整性的毒力产物的表达来保护 。这是首次报道外源添加的海藻酸盐会影响 的竞争，并部分解释了囊性纤维化中 与 共感染的现象。
