School of Food Science and Engineering, South China University of Technology, Guangzhou, 510640, P.R. China.
School of Bioscience and Bioengineering, South China University of Technology, Guangzhou, 510006, P.R. China.
Chembiochem. 2020 Jul 1;21(13):1852-1855. doi: 10.1002/cbic.202000035. Epub 2020 Mar 5.
Cyclohexane was directly oxy-functionalised to ϵ-caprolactone through a cascade reaction sequence combining visible-light-driven photocatalysis with cyclohexanone monooxygenase (CHMO) whole-cell biocatalysis. Two available photocatalysts, Au-doped TiO (Au-TiO ) and graphitic carbonitride (g-C N ), were evaluated in the experiment and some optimisations to the cascade reaction were applied. In stepwise mode, the highest degree of conversion from cyclohexanol to ϵ-caprolactone can be up to 41 %, with use of g-C N . The cascade reaction from cyclohexane to ϵ-caprolactone is achievable under a light intensity of 149 μW cm .
环己烷通过可见光驱动的光催化与环己酮单加氧酶（CHMO）全细胞生物催化相结合的级联反应序列，直接氧官能化生成ε-己内酯。实验中评估了两种可用的光催化剂，Au 掺杂的 TiO2（Au-TiO2）和石墨相氮化碳（g-C3N4），并对级联反应进行了一些优化。以逐步模式，使用 g-C3N4，环己醇到ε-己内酯的最高转化率可达 41%。在 149 μW·cm-2 的光强下，可以实现从环己烷到ε-己内酯的级联反应。
