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基于多物理场仿真的微针阵列电极经皮电神经刺激改善的研究。

Investigation of transcutaneous electrical nerve stimulation improvements with microneedle array electrodes based on multiphysics simulation.

机构信息

Biomedical Engineering Graduate Program, University of Manitoba, Winnipeg, Manitoba, Canada.

Electrical and Computer Engineering Department, University of Manitoba, Winnipeg, Manitoba, Canada.

出版信息

Int J Numer Method Biomed Eng. 2020 Mar;36(3):e3318. doi: 10.1002/cnm.3318. Epub 2020 Feb 18.

Abstract

This paper investigates microneedle array electrodes for transcutaneous electrical nerve stimulation, and compares their performance with conventional surface electrodes. A three-dimensional model of tissue was developed for finite element multiphysics simulations. Investigations included current density in different depths of a tissue, space constant under electrodes, specific absorption ratio of tissue, selectivity of stimulation, temperature rise, and blood flow. Results showed that microneedle electrodes have up to 10% higher selectivity than the surface electrodes. Furthermore, it was found that stimulation using microneedle electrodes provides more robust current density at different tissue depths compared to the surface electrode stimulation. Microneedle electrodes showed enhanced stimulation parameters, particularly for targeting a specific nerve in a specific depth of a tissue.

摘要

本文研究了用于经皮电神经刺激的微针阵列电极,并将其性能与传统的表面电极进行了比较。建立了一个组织的三维模型,用于有限元多物理场模拟。研究包括不同组织深度的电流密度、电极下的空间常数、组织的比吸收率、刺激的选择性、温升和血流。结果表明,微针电极的选择性比表面电极高 10%。此外,研究还发现,与表面电极刺激相比,使用微针电极刺激可以在不同的组织深度提供更稳定的电流密度。微针电极表现出增强的刺激参数,特别是在针对组织中特定深度的特定神经时。

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