Hernigou Philippe
Instr Course Lect. 2020;69:139-148.
Mesenchymal stem cells (MSCs) comprise a mixture of various stem cells in myeloid tissue with multipotential differentiation capacity. They can differentiate into bone cells under specific conditions and can be used to treat osteonecrosis of the femoral head through cell transplantation. This chapter summarizes research on MSCs in the field of osteonecrosis of the femoral head performed by our team, reveals the progress realized in the last 30 years, describes their potential to treat osteonecrosis disease, and analyzes existing challenges in the future for using MSCs in clinical applications.
间充质干细胞（MSCs）是骨髓组织中具有多向分化能力的多种干细胞的混合物。它们在特定条件下可分化为骨细胞，可通过细胞移植用于治疗股骨头坏死。本章总结了我们团队在股骨头坏死领域对间充质干细胞的研究，揭示了过去30年取得的进展，描述了它们治疗坏死性骨病的潜力，并分析了未来在临床应用中使用间充质干细胞存在的挑战。
