Nuvia Ltd, Approved Dosimetry Services, Harwell OX11 0RL, United Kingdom.
J Radiol Prot. 2020 Jun;40(2):444-464. doi: 10.1088/1361-6498/ab72df. Epub 2020 Feb 4.
Internal dose assessment intercomparison exercises are useful tools: to verify the performance of an internal dosimetry service; to promote the harmonisation of dose assessments; and to identify weaknesses where further improvements are necessary. However, no such international intercomparisons have been performed for more than ten years. In the period May 2014-May 2016, the 'Technical Recommendations for Monitoring Individuals for Occupational Intakes of Radionuclides' were developed on the initiative of the European Commission, and later published within the EC Radiation Protection series, as RP188. In 2017 the Working Group 'Internal Dosimetry' of the European Radiation Dosimetry Group (EURADOS) organised a new intercomparison action, named ICIDOSE 2017, with the main aim of testing the practical applicability of these technical recommendations (RP188). Four case studies were proposed to participants: an artificially created case of inhalation of Co to simulate a simple special monitoring case; a real case of inhalation of I, with simple routine monitoring; a real and more complex case of incorporation of U, featuring both confirmatory and special monitoring; and a complex real case of an accidental incorporation of Am, including multiple administrations of diethylenetriamine pentaacetic acid (DTPA). Results were received from 66 participants from 26 countries; these were compared to reference or recommended solutions, developed for each case based on the application of RP188. In cases 1, 2 and 4 only a small number of results were identified as outliers, with the spread of all the results, expressed as the geometric standard deviation (GSD) of the values, assessed as 1.07, 1.04 and 1.43, respectively. This observed spread of the submitted results was improved from those obtained from similar cases in previous intercomparison exercises, showing that the availability of RP188 contributes to the harmonisation of the internal dose assessment process. There was a much wider spread of results for the uranium case: this case was characterised by an absence of any prior knowledge of the exposure scenario, and participants assumed a range of different exposure pathways and patterns.
可以验证内部剂量测定服务的性能；促进剂量评估的协调一致；并确定需要进一步改进的弱点。然而，这种国际比对已经有十多年没有进行过了。在 2014 年 5 月至 2016 年 5 月期间，欧洲委员会倡议制定了《监测个人职业放射性核素摄入量的技术建议》，并随后在 EC 辐射防护系列中出版，编号为 RP188。2017 年，欧洲辐射剂量学组（EURADOS）的“内部剂量学”工作组组织了一次新的比对活动，名为 ICIDOSE 2017，主要目的是测试这些技术建议（RP188）的实际适用性。向参与者提出了四个案例研究：一个人为的吸入 Co 案例，用于模拟简单的特殊监测案例；一个真实的 I 吸入案例，进行简单的常规监测；一个真实的、更复杂的 U 摄入案例，包括确认性监测和特殊监测；以及一个复杂的 Am 意外摄入案例，包括多次使用二乙三胺五乙酸（DTPA）。从 26 个国家的 66 名参与者那里收到了结果；将这些结果与为每个案例基于 RP188 的应用而开发的参考或推荐解决方案进行了比较。在案例 1、2 和 4 中，只有少数结果被确定为异常值，所有结果的分布，用值的几何标准差（GSD）表示，分别评估为 1.07、1.04 和 1.43。与以前的比对活动中类似案例相比，提交结果的这种分布有所改善，表明 RP188 的可用性有助于内部剂量评估过程的协调一致。铀案例的结果分布要广泛得多：这个案例的特点是缺乏对暴露情况的任何事先了解，参与者假设了一系列不同的暴露途径和模式。
