一种摩尔质量为12千道尔顿的蛋白质整合到非洲猪瘟病毒感染细胞的膜中。
A protein of molar mass 12 kDa incorporates into the membrane of ASF virus-infected cells.
作者信息
Revilla Y, Pena L, Viñuela E
机构信息
Centro de Biología Molecular (CSIC-UAM), Facultad de Ciencias, Universidad Autónoma, Madrid, Spain.
出版信息
Virus Res. 1988 Sep;11(2):193-7. doi: 10.1016/0168-1702(88)90043-3.
PMID:3201826
Abstract
An African swine fever virus-induced protein of molar mass 12 kDa (p12) was studied in virus-infected Vero cells using the monoclonal antibody 18B.B11. Protein p12 is incorporated into the membrane of infected cells about 7 h post-infection and is not present in purified African swine fever virus particles. The synthesis of protein p12 is sensitive to cytosine arabinoside.
摘要
利用单克隆抗体18B.B11，在病毒感染的非洲绿猴肾细胞（Vero细胞）中对一种分子量为12千道尔顿的非洲猪瘟病毒诱导蛋白（p12）进行了研究。感染后约7小时，p12蛋白整合到受感染细胞的膜中，且不存在于纯化的非洲猪瘟病毒颗粒中。p12蛋白的合成对阿糖胞苷敏感。
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