Sarici S Ümit, Serdar Muhittin A, Dündaröz M Rusen, Ünay Bülent, Akin Ridvan, Deda Gülhis, Gökçay Erdal
Department of Pediatrics, Gülhane Military Medical Academy, Ankara, Turkey.
Department of Biochemistry, Gülhane Military Medical Academy, Ankara, Turkey.
Pediatr Neurol. 2001 Mar;24(3):205-208. doi: 10.1016/S0887-8994(00)00270-8.
Slight-to-moderate impairments may be observed in mental and motor developments of infants with iron- deficiency anemia. Brainstem auditory-evoked potentials provide a noninvasive means of examining the auditory aspect of the central nervous system functions. In this study the effect of iron-deficiency anemia on auditory functions was investigated by using brainstem auditory-evoked potentials. Brainstem auditory-evoked potentials of the 20 iron-deficient infants were not significantly different from those of the control group that included 20 healthy age-matched infants. Furthermore, there was not a statistically significant difference between the brainstem auditory-evoked potentials of the study group performed before and 3 months after oral iron therapy. Although we could not demonstrate a hearing loss in infants with moderate iron-deficiency anemia in this study, the relationship between severe iron-deficiency anemia and hearing loss or auditory dysfunction remains to be determined.
缺铁性贫血婴儿的智力和运动发育可能会出现轻度至中度受损。脑干听觉诱发电位提供了一种检查中枢神经系统功能听觉方面的非侵入性方法。在本研究中，通过使用脑干听觉诱发电位来研究缺铁性贫血对听觉功能的影响。20名缺铁婴儿的脑干听觉诱发电位与20名年龄匹配的健康婴儿组成的对照组相比，无显著差异。此外，研究组在口服铁剂治疗前和治疗3个月后的脑干听觉诱发电位之间也没有统计学上的显著差异。尽管在本研究中我们未能证实中度缺铁性贫血婴儿存在听力损失，但重度缺铁性贫血与听力损失或听觉功能障碍之间的关系仍有待确定。
