Medical Research Unit, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Aceh, Indonesia; Department of Family Medicine, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Aceh, Indonesia.
Department of Epidemiology, University of Michigan, Ann Arbor, Michigan, USA.
Vaccine. 2020 Mar 4;38(11):2592-2599. doi: 10.1016/j.vaccine.2020.01.072. Epub 2020 Feb 1.
Hesitancy towards vaccination has been studied as a barrier to vaccination among children, as well as participation in vaccine trials. This study aimed to investigate hesitancy towards vaccination among parents in Indonesia, as a part of the Indonesia Zika Vaccine Study.
A cross-sectional study was conducted in eleven regencies and municipalities in Aceh and West Sumatra province, Indonesia. Parents were recruited from families at outpatient clinics of community health centers or hospitals. The survey included various questions about sociodemographic factors and the Parent Attitudes about Childhood Vaccination (PACV) scale. Linear regression was employed to assess the association between explanatory variables and vaccine hesitancy.
A total of 956 parents were interviewed and 26.4% of participants had heard about Zika. Overall, 152 parents (15.9%) were vaccine hesitant, and this proportion was the highest in the safety and efficacy subdomain (61.6%). In the unadjusted analysis, having a diploma certificate, working in the health sector, and having heard about Zika were significantly associated with non-hesitancy towards children vaccination. Having heard about Zika was the only factor that was significantly associated with hesitancy towards vaccination in multivariate model (aOR: 0.43, 95% CI: 0.26-0.71). Mothers, younger parents (aged 20-29 years old), and those with only a primary school education were more concerned about vaccine safety and efficacy compared to fathers, older groups, and individuals with more education, respectively.
Hesitancy towards pediatric vaccination is observed in 15% of respondents and most of the hesitancy was expressed in terms of vaccine safety and efficacy. Therefore, continuous dissemination of vaccine information needs to be carried out to earn parents' trust and increase vaccination coverage in Indonesia.
在儿童疫苗接种中，对接种犹豫不决的研究既包括疫苗接种，也包括疫苗试验参与。本研究旨在调查印度尼西亚父母对接种疫苗的犹豫程度，这是印度尼西亚寨卡疫苗研究的一部分。
在印度尼西亚亚齐省和西苏门答腊省的 11 个县和市进行了一项横断面研究。从社区卫生中心或医院的门诊诊所的家庭中招募父母。该调查包括各种关于社会人口因素和儿童疫苗接种家长态度（PACV）量表的问题。线性回归用于评估解释变量与疫苗犹豫之间的关系。
共采访了 956 位父母，其中 26.4%的参与者听说过寨卡病毒。总的来说，有 152 位父母（15.9%）对接种疫苗犹豫不决，在安全性和有效性子领域的比例最高（61.6%）。在未调整的分析中，拥有文凭证书、在卫生部门工作和听说过寨卡病毒与儿童疫苗接种不犹豫显著相关。听说过寨卡病毒是唯一与多变量模型中接种疫苗犹豫不决显著相关的因素（调整后的比值比：0.43，95%可信区间：0.26-0.71）。与父亲、年龄较大的群体和受教育程度较高的个体相比，母亲、年龄在 20-29 岁之间的年轻父母以及仅接受过小学教育的父母更关心疫苗的安全性和有效性。
在 15%的受访者中观察到对接种疫苗的犹豫，并且大多数犹豫是在疫苗安全性和有效性方面。因此，需要持续传播疫苗信息，以赢得父母的信任并提高印度尼西亚的疫苗接种率。
