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沙特阿拉伯心脏手术后胸骨伤口感染的发生率、类型和结局。一项回顾性病历回顾研究。

Incidence, types and outcomes of sternal wound infections after cardiac surgery in Saudi Arabia. A retrospective medical chart review.

机构信息

Department of Infectious Diseases, King Saudi University, Riyadh, Kingdom of Saudi Arabia. E-mail.

出版信息

Saudi Med J. 2020 Feb;41(2):177-182. doi: 10.15537/smj.2020.2.24843.

Abstract

To determine the incidence, types, risk factors, identify organisms, and assess outcomes of surgical wound infections (SWIs) after cardiac surgery at a tertiary hospital in Riyadh, Saudi Arabia. Methods: This historical cohort study reviewed the chart of  patients who underwent cardiac surgery at King Khalid University Hospital, Riyadh, Saudi Arabia between January 2009 and December 2014. The proforma contained personal data, comorbidities, type of surgery, microbiological analysis, and management outcomes. Results: A total of 1241 patients were enrolled in the study comprising 1,032 (83.2%) men and 209 (16.8%) women. Forty (3.2%) patients developed SWI, of which 32 (2.5%) were superficial and 8 (0.7%) were deep. Gender, obesity, diabetes mellitus, non-use of statins, and coronary artery bypass graft (CABG) surgery were not significant predictors of infection in the study. Methicillin-susceptible Staphylococcus aureus was isolated predominantly in 45%, followed by Klebsiella and Pseudomonas species. Methicillin-resistant Staphylococcus aureus, Enterococcus faecium, and extended β-lactamase-producing gram-negative organisms were pathogens isolated in last 3 years of the review.  Simple and vacuum assisted closure therapies led to complete resolution in 32 (80%) patients, while 8 (20%) developed sternal osteomyelitis. All patients survived except one with a deep SWI who died of uncontrolled sepsis.  Conclusion: Despite the low incidence of postoperative SWIs, the risk of sternal osteomyelitis development persists. Meticulous choice of CABG components and appropriate postoperative management, especially detecting early signs of SWI could contribute to lower its incidence and complications.

摘要

目的

在沙特阿拉伯利雅得的一家三级医院确定心脏手术后外科伤口感染(SWI)的发生率、类型、危险因素、病原体以及评估结局。

方法

这是一项回顾性队列研究,对 2009 年 1 月至 2014 年 12 月期间在沙特阿拉伯利雅得的哈立德国王大学医院接受心脏手术的患者的病历进行了回顾。该表格包含个人数据、合并症、手术类型、微生物分析和管理结局。

结果

共纳入 1241 例患者,其中 1032 例(83.2%)为男性,209 例(16.8%)为女性。40 例(3.2%)患者发生了 SWI,其中 32 例(2.5%)为浅表性感染,8 例(0.7%)为深部感染。在该研究中,性别、肥胖、糖尿病、不使用他汀类药物和冠状动脉旁路移植术(CABG)并不是感染的显著预测因素。耐甲氧西林金黄色葡萄球菌主要分离出 45%,其次是克雷伯菌和假单胞菌。耐甲氧西林金黄色葡萄球菌、粪肠球菌和产 extended β-lactamase 的革兰氏阴性菌是在回顾的最后 3 年中分离出的病原体。单纯和真空辅助闭合治疗使 32 例(80%)患者完全治愈,而 8 例(20%)患者发生胸骨骨髓炎。除 1 例深部 SWI 患者因无法控制的败血症死亡外,所有患者均存活。

结论

尽管术后 SWI 的发生率较低,但胸骨骨髓炎发展的风险仍然存在。仔细选择 CABG 组件和适当的术后管理,特别是早期发现 SWI 的迹象,可能有助于降低其发生率和并发症。

相似文献

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Epidemiology of deep sternal wound infection in cardiac surgery.心脏手术中深部胸骨伤口感染的流行病学
J Cardiothorac Vasc Anesth. 2009 Aug;23(4):488-94. doi: 10.1053/j.jvca.2009.02.007. Epub 2009 Apr 19.

本文引用的文献

1
CABG: A continuing evolution.冠状动脉旁路移植术(CABG):持续演进。
Cleve Clin J Med. 2017 Dec;84(12 Suppl 4):e15-e19. doi: 10.3949/ccjm.84.s4.04.

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