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卡芬太尼在物质使用障碍患者治疗中的应用。

Carfentanil Use in a Patient Undergoing Treatment for Substance Use Disorder.

机构信息

Behavioral Enhancement and Substance Abuse Treatment, PLLC, Deer Park, NY.

Truetox Laboratories, LLC, Garden City Park, NY.

出版信息

J Anal Toxicol. 2020 Jul 31;44(6):618-622. doi: 10.1093/jat/bkaa011.

Abstract

Carfentanil is a synthetic opioid approximately 10,000 times as powerful as morphine. It is not approved for human use. However, cases of death associated with carfentanil have become more frequent in recent years. In this report, the case of a patient with a positive urine test for norcarfentanil (a metabolite of carfentanil) is described. The analytical method leading to the detection is summarized. This is a rarely reported case of survival of carfentanil use. It is unique in the published literature of an account of a norcarfentanil-positive patient concurrently enrolled in a substance use disorder treatment program. To the authors' knowledge, this is the first documented case of a carfentanil exposure in the state of New York.

摘要

卡芬太尼是一种合成阿片类药物,效力大约是吗啡的 10000 倍。它未获准供人类使用。然而,近年来与卡芬太尼相关的死亡案例变得更加频繁。在本报告中,描述了一例尿液检测到去甲卡芬太尼(卡芬太尼的代谢物)呈阳性的患者。总结了导致检测的分析方法。这是卡芬太尼使用后存活的罕见案例。在已发表的文献中,同时报告了去甲卡芬太尼阳性患者接受物质使用障碍治疗的案例,这是一个独特的案例。据作者所知,这是纽约州首例有记录的卡芬太尼暴露案例。

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