Rywik S, Kupść W, Wagrowska H, Kulesza W, Broda G, Polakowska M
Department of Epidemiology, National Institute of Cardiology, Warsaw, Poland.
Acta Med Scand Suppl. 1988;728:95-105. doi: 10.1111/j.0954-6820.1988.tb05560.x.
The present study, based on the World Health Organization (WHO) MONICA Project design, covers two Warsaw districts inhabited by 274442 people, aged 25-64. In the studied population over the years 1976-1985, no significant time-trends were found of cardiovascular disease (CVD), ischemic heart disease (IHD), myocardial infarction (MI) and cerebrovascular mortality, whereas the hypertension mortality trends increased significantly. The MI attack rate in 1984/85 in men aged 25-64 was 466/100,000 and that of women 173/100,000. Within the last 14-15 years the age-standardized MI attack rates increased by 35% in men aged 35-64 and by 65% in women. The 28-day case fatality was 40% in men and 35% in women. Fatality was highest the first day after the onset of symptoms, and only 66% of men and 72% of women survived the first 3 days after onset. No significant differences in age-standardized mean values of plasma total cholesterol, low-density lipoprotein (LDL)-cholesterol and systolic blood pressure (BP) were found between men and women. Mean values of high-density lipoprotein-cholesterol (HDL) and of the Quatelet index were higher in the female population, whereas the triglyceride level, diastolic BP, and the number of cigarettes smoked daily were higher in the male population. In men, the plasma total cholesterol, LDL-cholesterol and HDL-cholesterol values did not change with age, but the tryglyceride values decreased; in women, the plasma total cholesterol, LDL-cholesterol and triglyceride values increased with age. Mean values of systolic and diastolic BP increased with age in both sexes, whereas the number of cigarettes smoked daily decreased.
本研究基于世界卫生组织（WHO）的莫尼卡项目设计，涵盖华沙的两个区，居住着274442名年龄在25至64岁之间的居民。在1976年至1985年期间的研究人群中，未发现心血管疾病（CVD）、缺血性心脏病（IHD）、心肌梗死（MI）和脑血管疾病死亡率有显著的时间趋势，而高血压死亡率趋势显著上升。1984/85年，25至64岁男性的MI发病率为466/10万，女性为173/10万。在过去14至15年中，35至64岁男性的年龄标准化MI发病率增加了35%，女性增加了65%。28天病死率男性为40%，女性为35%。症状出现后的第一天病死率最高，症状出现后的前3天，只有66%的男性和72%的女性存活。男性和女性之间血浆总胆固醇、低密度脂蛋白（LDL）胆固醇和收缩压（BP）的年龄标准化均值无显著差异。女性人群中高密度脂蛋白胆固醇（HDL）均值和体重指数较高，而男性人群中甘油三酯水平、舒张压和每日吸烟量较高。男性的血浆总胆固醇、LDL胆固醇和HDL胆固醇值不随年龄变化，但甘油三酯值下降；女性的血浆总胆固醇、LDL胆固醇和甘油三酯值随年龄增加。男女收缩压和舒张压均值均随年龄增加，而每日吸烟量下降。
