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尼泊尔特库医院抗逆转录病毒治疗诊所中艾滋病毒感染者的生育意愿及其决定因素

Fertility Desire and Its Determinants Among People Living with HIV in Antiretroviral Therapy Clinic of Teku Hospital, Nepal.

作者信息

Shrestha Namuna, Pokharel Rajani, Poudyal Anil, Subedi Ranjeeta, Mahato Namra Kumar, Gautam Nitisha, Kc Dirghayu, Dhungana Govinda Prasad

机构信息

Chitwan Medical College, Chitwan, Nepal.

Maharajgunj Medical Campus, Maharajgunj, Kathmandu, Nepal.

出版信息

HIV AIDS (Auckl). 2020 Jan 15;12:41-46. doi: 10.2147/HIV.S235502. eCollection 2020.

DOI:10.2147/HIV.S235502
PMID:32021485
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6970249/
Abstract

BACKGROUND

Pregnancy in people Living with HIV/AIDS (PLHIV) involves significant public health risks, including the risk of HIV transmission to uninfected partners and the fetus. Despite the growing importance of fertility issues for HIV-infected people, little is known about their fertility desires in Nepal. This study, therefore, aimed to determine the magnitude of and factors associated with the fertility desire of PLHIV.

PATIENTS AND METHODS

A cross-sectional study was conducted among 280 PLHIV attending the antiretroviral therapy (ART) clinic in Teku Hospital, Nepal. A standard semi-structured questionnaire was administered to participants using systematic random sampling. Data were entered using Epi-data 3.1 and analyzed using SPSS software version 20.

RESULTS

Out of the total participants, 12.1% desired to have a child. Among those having this desire, 44.1% had not decided when to have a child. Reasons for desiring a child were having no children (44.1%), wanting to have a child of different sex than the previous one (29.4%), followed by wanting to have another child (26.5%). Factors such as being male (COR: 3.1, 95% CI: 1.3-7.0), being ≤40 years of age (COR: 3.8, 95% CI: 1.5-9.4), higher age at marriage (COR: 7.7, 95% CI: 1.5-39.6), middle socio-economic status (COR: 3.5, 95% CI: 1.7-7.3), having no children (COR: 22.9, 95% CI: 8.6-60.8) or fewer children (COR: 74.8, 95% CI: 9.7-575.1), greater CD4 count (COR: 2.8, 95% CI: 1.3-5.9) and having moderate knowledge of prevention of mother-to-child transmission (COR: 5.4, 95% CI: 2.3-12.7) had higher odds of having fertility desire.

CONCLUSION

Around one in every ten participants had a desire for fertility despite their HIV status. This calls for special attention in promoting integrated services for HIV and reproductive health. It will be important to include counseling and other services for those with fertility desire alongside providing ART.

摘要

背景

感染艾滋病毒/艾滋病的人(PLHIV)怀孕涉及重大公共卫生风险,包括将艾滋病毒传播给未感染伴侣和胎儿的风险。尽管生育问题对艾滋病毒感染者日益重要,但在尼泊尔,人们对他们的生育愿望知之甚少。因此,本研究旨在确定艾滋病毒感染者生育愿望的程度及其相关因素。

患者与方法

在尼泊尔特库医院接受抗逆转录病毒治疗(ART)门诊的280名艾滋病毒感染者中进行了一项横断面研究。采用系统随机抽样方法,向参与者发放标准的半结构化问卷。数据使用Epi - data 3.1录入,并使用SPSS软件20版进行分析。

结果

在所有参与者中,12.1%的人希望生育孩子。在有此愿望的人中,44.1%尚未决定何时生育。想要孩子的原因是没有孩子(44.1%)、想要一个与前一个孩子性别不同的孩子(29.4%),其次是想要再生一个孩子(26.5%)。男性(校正比值比:3.1,95%置信区间:1.3 - 7.0)、年龄≤40岁(校正比值比:3.8,95%置信区间:1.5 - 9.4)、结婚年龄较大(校正比值比:7.7,95%置信区间:1.5 - 39.6)、中等社会经济地位(校正比值比:3.5,95%置信区间:1.7 - 7.3)、没有孩子(校正比值比:22.9,95%置信区间:8.6 - 60.8)或孩子较少(校正比值比:74.8,95%置信区间:9.7 - 575.1)、CD4细胞计数较高(校正比值比:2.8,95%置信区间:1.3 - 5.9)以及对预防母婴传播有中等程度的了解(校正比值比:5.4,95%置信区间:2.3 - 12.7)的人有更高的生育愿望几率。

结论

尽管感染艾滋病毒,但每十名参与者中约有一人有生育愿望。这就要求在促进艾滋病毒与生殖健康综合服务方面给予特别关注。除了提供抗逆转录病毒治疗外,为有生育愿望的人提供咨询和其他服务也很重要。

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