勿被脂肪迷惑：一例罕见的伴有瘤内脂肪的肾细胞癌

Don't be fooled by the fat: A rare case of renal cell carcinoma with intratumoural fat.

作者信息

Morris Hannah, March Brayden, Delprado Warick, McLeod Nicholas

机构信息

Department of Urology, John Hunter Hospital, New Lambton Heights, NSW, 2305, Australia.

School of Medicine and Public Health, Faculty of Health and Medicine, University of Newcastle, Callaghan, NSW, 2308, Australia.

出版信息

Urol Case Rep. 2019 Dec 27;30:101112. doi: 10.1016/j.eucr.2019.101112. eCollection 2020 May.

DOI:10.1016/j.eucr.2019.101112

PMID:32021805

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6992983/

Abstract

Angiomyolipoma (AML) is a benign renal tumour composed of fat, smooth muscle and blood vessels. Radiologic evidence of macroscopic fat within a solid renal lesion on computed tomography was historically thought to be pathognomonic for this condition. Herein, we report a case of an incidental solid renal cell mass with multiple foci of intra-tumoral fat, which was shown to be a clear cell renal cell carcinoma (RCC) at nephrectomy. Macroscopic fat within solid renal lesions does not exclude malignancy, evaluation of other radiologic features is necessary when RCC is suspected.

摘要

血管平滑肌脂肪瘤（AML）是一种由脂肪、平滑肌和血管组成的良性肾肿瘤。计算机断层扫描显示实性肾病变内存在肉眼可见脂肪的放射学证据，历来被认为是这种疾病的特征性表现。在此，我们报告一例偶然发现的实性肾细胞肿块病例，该肿块内有多个瘤内脂肪灶，肾切除术后病理显示为透明细胞肾细胞癌（RCC）。实性肾病变内的肉眼可见脂肪并不能排除恶性肿瘤的可能，当怀疑为肾细胞癌时，有必要评估其他放射学特征。