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葡萄牙急性失代偿性心力衰竭结局的真实世界分析。

Real-world analysis of acute decompensated heart failure outcomes in Portugal.

作者信息

Marques-Alves Patrícia, Marinho Ana Vera, Almeida José Paulo, Gonçalves Tatiana, Costa Marta, Ferreira Mafalda, Baptista Rui, Costa Susana, Franco Fátima, Fonseca Isabel, Gonçalves Lino

机构信息

Department of Cardiology, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal.

Faculty of Medicine, University of Coimbra, Coimbra, Portugal.

出版信息

ESC Heart Fail. 2020 Apr;7(2):551-558. doi: 10.1002/ehf2.12599. Epub 2020 Feb 5.

Abstract

AIMS

In Portugal, in the last 5 years, no study has published recent data regarding outcomes of patients with acute decompensated heart failure (ADHF). We aimed to determine the characteristics and outcomes of a large contemporaneous Portuguese cohort of ADHF patients admitted to our emergency department (ED).

METHODS AND RESULTS

We conducted a retrospective, study of all 1024 patients admitted to our ED with a discharge diagnosis of ADHF from November 2016 to December 2017. Baseline clinical data and outcomes {in-hospital, 30 day, and follow-up all-cause mortality, and readmissions; median follow-up, 5 months; interquartile range [(IQR), 3-11 months]} were determined. Mean age was 78 ± 10 years, and 53% were male; of the 1024 patients, 554 (54%) were hospitalized. The median hospitalization length was 9 (IQR, 5-15) days, and in-hospital mortality was 12.7%. Hospitalized patients were predominantly men (56% vs. 47%; P < 0.001), younger (77 ± 9 vs. 79 ± 11 years; P = 0.002) and had higher creatinine values and B-type natriuretic peptide values (P < 0.001) than discharged patients. Patients with prior hospitalization had lower 30 day readmission rate (8% vs. 14%; P = 0.01), same overall readmission rate (30% vs. 32%), and higher 30 day (13% vs. 5%; P < 0.001) and overall mortality rates (28% vs. 15%; P < 0.001).

CONCLUSIONS

Approximately half of the patients admitted to the ED were hospitalized. Of these, only 8% were readmitted in the ED within 30 days. The clinical and analytical status in the ED are important predictors of hospitalization.

摘要

目的

在葡萄牙,过去5年中,尚无研究发表关于急性失代偿性心力衰竭(ADHF)患者预后的最新数据。我们旨在确定我院急诊科收治的大量同期葡萄牙ADHF患者队列的特征和预后。

方法与结果

我们对2016年11月至2017年12月期间我院急诊科收治的1024例出院诊断为ADHF的患者进行了回顾性研究。确定基线临床数据和预后情况(住院期间、30天、随访全因死亡率及再入院情况;中位随访时间为5个月;四分位间距[(IQR),3 - 11个月])。平均年龄为78±10岁,53%为男性;1024例患者中,554例(54%)住院治疗。中位住院时长为9(IQR,5 - 15)天,住院死亡率为12.7%。住院患者以男性为主(56%对47%;P < 0.001),年龄较轻(77±9岁对79±11岁;P = 0.002),且肌酐值和B型利钠肽值高于出院患者(P < 0.001)。既往有住院史的患者30天再入院率较低(8%对14%;P = 0.01),总体再入院率相同(30%对32%),30天死亡率(13%对5%;P < 0.001)和总体死亡率较高(28%对15%;P < 0.001)。

结论

急诊科收治的患者中约一半住院治疗。其中,仅8%在30天内再次入住急诊科。急诊科的临床和分析状况是住院的重要预测因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7a3/7160503/bebc8ee8e912/EHF2-7-551-g001.jpg

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