Price C, Jacocks M A, Tytle T
Department of Surgery, University of Oklahoma Health Sciences Center, Oklahoma City.
Am J Surg. 1988 Dec;156(6):488-91. doi: 10.1016/s0002-9610(88)80536-1.
The courses of 17 patients who underwent 20 separate attempts at thrombolysis for acute arterial thrombosis are reviewed to clarify the safety and efficacy of this therapy. Seventeen of 20 thrombolyses were angiographically successful. Patients who had correctable lesions identified and reconstructive procedures performed tended to do better than those who did not, and patients who had successful thrombolysis tended to have fewer and less radical amputations. Complications can be reduced by careful, close monitoring of patients undergoing therapy.
回顾了17例接受20次急性动脉血栓形成溶栓独立尝试的患者病程，以阐明该治疗方法的安全性和有效性。20次溶栓中有17次血管造影成功。发现有可纠正病变并进行重建手术的患者往往比未进行此类操作的患者情况更好，且溶栓成功的患者截肢次数往往更少，程度也更轻。通过对接受治疗的患者进行仔细、密切的监测，可以减少并发症的发生。
