• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Zig Zag AFM Protocol Reveals New Intermediate Folding States of Bacteriorhodopsin.

作者信息

Nash Michael A

机构信息

Institute of Physical Chemistry, Department of Chemistry, University of Basel, Basel, Switzerland; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland.

出版信息

Biophys J. 2020 Feb 4;118(3):538-540. doi: 10.1016/j.bpj.2019.12.004. Epub 2019 Dec 13.

DOI:10.1016/j.bpj.2019.12.004
PMID:32023441
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7002909/
Abstract
摘要

相似文献

1
Zig Zag AFM Protocol Reveals New Intermediate Folding States of Bacteriorhodopsin.锯齿形原子力显微镜协议揭示了细菌视紫红质新的中间折叠状态。
Biophys J. 2020 Feb 4;118(3):538-540. doi: 10.1016/j.bpj.2019.12.004. Epub 2019 Dec 13.
2
Quantifying the Initial Unfolding of Bacteriorhodopsin Reveals Retinal Stabilization.定量研究细菌视紫红质的初始展开揭示了视黄醛的稳定化。
Angew Chem Int Ed Engl. 2019 Feb 4;58(6):1710-1713. doi: 10.1002/anie.201812072. Epub 2019 Jan 9.
3
Hidden dynamics in the unfolding of individual bacteriorhodopsin proteins.细菌视紫红质蛋白个体展开过程中的隐藏动力学。
Science. 2017 Mar 3;355(6328):945-950. doi: 10.1126/science.aah7124.
4
Phase II study of sequential high-dose methotrexate and fluorouracil combined with doxorubicin as a neoadjuvant chemotherapy for scirrhous gastric cancer.序贯大剂量甲氨蝶呤和氟尿嘧啶联合阿霉素作为硬癌型胃癌新辅助化疗的II期研究
Gastric Cancer. 2001;4(4):192-7. doi: 10.1007/s10120-001-8009-5.
5
Phase I-II study of 5-fluorouracil, leucovorin, doxorubicin, methotrexate, and long-term oral etoposide (FLAME) in unresectable or metastatic gastric cancer.
Am J Clin Oncol. 1998 Dec;21(6):537-42. doi: 10.1097/00000421-199812000-00001.
6
Doxorubicin in combination with fluorouracil and cyclophosphamide (i.v. FAC regimen, day 1, 21) versus methotrexate in combination with fluorouracil and cyclophosphamide (i.v. CMF regimen, day 1, 21) as adjuvant chemotherapy for operable breast cancer: a study by the GEICAM group.多柔比星联合氟尿嘧啶和环磷酰胺（静脉注射FAC方案，第1天、第21天）与甲氨蝶呤联合氟尿嘧啶和环磷酰胺（静脉注射CMF方案，第1天、第21天）作为可手术乳腺癌辅助化疗的比较：GEICAM组的一项研究
Ann Oncol. 2003 Jun;14(6):833-42. doi: 10.1093/annonc/mdg260.
7
Doxorubicin/methotrexate/fluorouracil in advanced pancreatic cancer.
Lancet. 1990 Dec 8;336(8728):1454-5. doi: 10.1016/0140-6736(90)93168-o.
8
Doxorubicin followed by cyclophosphamide, methotrexate, and fluorouracil for breast cancer.
JAMA. 1995 Sep 13;274(10):796-7. doi: 10.1001/jama.274.10.796.
9
Sequential high-dose methotrexate, 5-fluorouracil, and doxorubicin for treatment of advanced pancreatic cancer.序贯大剂量甲氨蝶呤、5-氟尿嘧啶和阿霉素治疗晚期胰腺癌。
J Cancer Res Clin Oncol. 1990;116(2):132-3. doi: 10.1007/BF01612666.
10
Doxorubicin versus methotrexate both combined with cyclophosphamide, 5-fluorouracil and tamoxifen in postmenopausal patients with advanced breast cancer--a randomised study with more than 10 years follow-up from the Danish Breast Cancer Cooperative Group. Danish Breast Cancer Cooperative Group (DBCG).多柔比星与甲氨蝶呤分别联合环磷酰胺、5-氟尿嘧啶和他莫昔芬用于绝经后晚期乳腺癌患者的疗效比较——丹麦乳腺癌协作组超过10年随访的随机研究。丹麦乳腺癌协作组（DBCG）
Eur J Cancer. 1999 Jan;35(1):39-46. doi: 10.1016/s0959-8049(98)00354-2.

引用本文的文献

1
Next Generation Methods for Single-Molecule Force Spectroscopy on Polyproteins and Receptor-Ligand Complexes.多聚蛋白和受体-配体复合物单分子力谱的下一代方法
Front Mol Biosci. 2020 May 19;7:85. doi: 10.3389/fmolb.2020.00085. eCollection 2020.

本文引用的文献

1
Membrane-Protein Unfolding Intermediates Detected with Enhanced Precision Using a Zigzag Force Ramp.使用锯齿形力斜坡以更高精度检测膜蛋白展开中间体。
Biophys J. 2020 Feb 4;118(3):667-675. doi: 10.1016/j.bpj.2019.12.003. Epub 2019 Dec 13.
2
Force Spectroscopy with 9-μs Resolution and Sub-pN Stability by Tailoring AFM Cantilever Geometry.通过定制原子力显微镜（AFM）悬臂梁几何结构实现具有9微秒分辨率和亚皮牛稳定性的力谱分析。
Biophys J. 2017 Dec 19;113(12):2595-2600. doi: 10.1016/j.bpj.2017.10.023. Epub 2017 Nov 11.
3
Hidden dynamics in the unfolding of individual bacteriorhodopsin proteins.细菌视紫红质蛋白个体展开过程中的隐藏动力学。
Science. 2017 Mar 3;355(6328):945-950. doi: 10.1126/science.aah7124.
4
Single-molecule force spectroscopy on polyproteins and receptor-ligand complexes: The current toolbox.多聚蛋白和受体-配体复合物的单分子力谱：当前的工具箱
J Struct Biol. 2017 Jan;197(1):3-12. doi: 10.1016/j.jsb.2016.02.011. Epub 2016 Feb 9.
5
Bacteriorhodopsin folds into the membrane against an external force.细菌视紫红质在外力作用下折叠进入膜内。
J Mol Biol. 2006 Mar 24;357(2):644-54. doi: 10.1016/j.jmb.2005.12.065. Epub 2006 Jan 6.
6
Molecular force modulation spectroscopy revealing the dynamic response of single bacteriorhodopsins.分子力调制光谱揭示单个细菌视紫红质的动态响应
Biophys J. 2005 Feb;88(2):1423-31. doi: 10.1529/biophysj.104.052746. Epub 2004 Dec 1.
7
Stepwise unfolding of titin under force-clamp atomic force microscopy.在力钳原子力显微镜下肌联蛋白的逐步展开
Proc Natl Acad Sci U S A. 2001 Jan 16;98(2):468-72. doi: 10.1073/pnas.98.2.468. Epub 2001 Jan 9.
8
Unfolding pathways of individual bacteriorhodopsins.单个细菌视紫红质的解折叠途径
Science. 2000 Apr 7;288(5463):143-6. doi: 10.1126/science.288.5463.143.
9
Reversible unfolding of individual titin immunoglobulin domains by AFM.通过原子力显微镜对肌联蛋白单个免疫球蛋白结构域进行可逆解折叠
Science. 1997 May 16;276(5315):1109-12. doi: 10.1126/science.276.5315.1109.