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一种 Guillain-Barré 综合征的眼咽亚型,不累及滑车神经和展神经。

An Oculopharyngeal Subtype of Guillain-Barré Syndrome Sparing the Trochlear and Abducens Nerves.

作者信息

Arakawa Masafumi, Yamazaki Mineo, Toda Yusuke, Ozawa Akiko, Kimura Kazumi

机构信息

Department of Neurology, Nippon Medical School Chiba Hokusoh Hospital, Japan.

出版信息

Intern Med. 2020 May 1;59(9):1215-1217. doi: 10.2169/internalmedicine.3395-19. Epub 2020 Feb 5.

Abstract

Guillain-Barré syndrome (GBS) comprises a group of polyneuropathies characterized by rapid progression of limb paralysis. Various subtypes of GBS have been reported. The oculopharyngeal subtype of GBS is currently understood to be primarily a cranial polyneuropathy without limb weakness or cerebellar ataxia. In our case of 62-year-old man, gastrointestinal infection was followed by paranesthesia of the hands. He had bilateral ptosis, pharyngeal disorder, and tongue and bifacial weakness. We diagnosed oculopharyngeal subtype of GBS. It responded to intravenous immunoglobulin. This case highlights the need for further characterization of unusual GBS subtypes.

摘要

吉兰-巴雷综合征(GBS)是一组以肢体麻痹快速进展为特征的多发性神经病。已报道了GBS的多种亚型。目前认为GBS的眼咽型主要是一种无肢体无力或小脑共济失调的颅部多发性神经病。在我们这个62岁男性的病例中,胃肠道感染后出现手部感觉异常。他有双侧上睑下垂、咽部功能障碍以及舌部和双侧面肌无力。我们诊断为GBS的眼咽型。该病例对静脉注射免疫球蛋白有反应。此病例凸显了进一步明确不寻常GBS亚型特征的必要性。

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