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[Mechanism of STAT3 phosphorylation mediated leukemia cells resistance to doxorubicin].

作者信息

Jia Z X, Lu X Z, Cai X H, Qin W, Han W M, Xiao R, Zhou M, Xu W

机构信息

Department of Hematology, the Affiliated Hospital of Nanjing Medical University, Changzhou No.2 People's Hospital, Changzhou 213000, China; Department of Hematology, the First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, Nanjing 210029, China.

Department of Hematology, the Affiliated Hospital of Nanjing Medical University, Changzhou No.2 People's Hospital, Changzhou 213000, China.

出版信息

Zhonghua Xue Ye Xue Za Zhi. 2020 Jan 14;41(1):69-71. doi: 10.3760/cma.j.issn.0253-2727.2020.01.013.

DOI:10.3760/cma.j.issn.0253-2727.2020.01.013
PMID:32023758
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7357914/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b2e/7357914/5f91a35c4a73/cjh-41-01-069-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b2e/7357914/f6fe16c07609/cjh-41-01-069-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b2e/7357914/756923c19238/cjh-41-01-069-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b2e/7357914/4004f6d94d8b/cjh-41-01-069-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b2e/7357914/5f7a1ad5dac4/cjh-41-01-069-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b2e/7357914/5f91a35c4a73/cjh-41-01-069-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b2e/7357914/f6fe16c07609/cjh-41-01-069-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b2e/7357914/756923c19238/cjh-41-01-069-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b2e/7357914/4004f6d94d8b/cjh-41-01-069-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b2e/7357914/5f7a1ad5dac4/cjh-41-01-069-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b2e/7357914/5f91a35c4a73/cjh-41-01-069-g005.jpg

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本文引用的文献

1
Inorganic kernel - Supported asymmetric hybrid vesicles for targeting delivery of STAT3-decoy oligonucleotides to overcome anti-HER2 therapeutic resistance of BT474R.无机核 - 支持不对称杂化囊泡用于靶向递送 STAT3 诱饵寡核苷酸，以克服 BT474R 对抗 HER2 治疗的耐药性。
J Control Release. 2018 Jun 10;279:53-68. doi: 10.1016/j.jconrel.2018.04.023. Epub 2018 Apr 12.
2
Parthenolide facilitates apoptosis and reverses drug-resistance of human gastric carcinoma cells by inhibiting the STAT3 signaling pathway.小白菊内酯通过抑制信号转导与转录激活因子3（STAT3）信号通路促进人胃癌细胞凋亡并逆转其耐药性。
Oncol Lett. 2018 Mar;15(3):3572-3579. doi: 10.3892/ol.2018.7739. Epub 2018 Jan 8.
3
SH003 reverses drug resistance by blocking signal transducer and activator of transcription 3 (STAT3) signaling in breast cancer cells.
SH003 通过阻断乳腺癌细胞中的信号转导子和转录激活子 3（STAT3）信号来逆转耐药性。
Biosci Rep. 2017 Nov 15;37(6). doi: 10.1042/BSR20170125. Print 2017 Dec 22.
4
Solanum nigrum Unripe fruit fraction attenuates Adriamycin resistance by down-regulating multi-drug resistance protein (Mdr)-1 through Jak-STAT pathway.龙葵未成熟果实提取物通过Jak-STAT信号通路下调多药耐药蛋白1（Mdr-1）来减弱阿霉素耐药性。
BMC Complement Altern Med. 2017 Jul 18;17(1):370. doi: 10.1186/s12906-017-1872-3.
5
Combined targeting of STAT3 and STAT5: a novel approach to overcome drug resistance in chronic myeloid leukemia.联合靶向 STAT3 和 STAT5：克服慢性髓性白血病耐药性的新方法。
Haematologica. 2017 Sep;102(9):1519-1529. doi: 10.3324/haematol.2016.163436. Epub 2017 Jun 8.
6
STAT3 mediates multidrug resistance of Burkitt lymphoma cells by promoting antioxidant feedback.信号转导和转录激活因子3（STAT3）通过促进抗氧化反馈介导伯基特淋巴瘤细胞的多药耐药性。
Biochem Biophys Res Commun. 2017 Jun 17;488(1):182-188. doi: 10.1016/j.bbrc.2017.05.031. Epub 2017 May 5.
7
Secreted GRP78 activates EGFR-SRC-STAT3 signaling and confers the resistance to sorafeinib in HCC cells.分泌型GRP78激活EGFR-SRC-STAT3信号通路并赋予肝癌细胞对索拉非尼的抗性。
Oncotarget. 2017 Mar 21;8(12):19354-19364. doi: 10.18632/oncotarget.15223.
8
Exploration of 2-((Pyridin-4-ylmethyl)amino)nicotinamide Derivatives as Potent Reversal Agents against P-Glycoprotein-Mediated Multidrug Resistance.探索2-((吡啶-4-基甲基)氨基)烟酰胺衍生物作为针对P-糖蛋白介导的多药耐药性的有效逆转剂。
J Med Chem. 2017 Apr 13;60(7):2930-2943. doi: 10.1021/acs.jmedchem.6b01879. Epub 2017 Mar 24.
9
Feedback Activation of STAT3 as a Cancer Drug-Resistance Mechanism.反馈激活 STAT3 作为癌症耐药机制。
Trends Pharmacol Sci. 2016 Jan;37(1):47-61. doi: 10.1016/j.tips.2015.10.001. Epub 2015 Nov 12.
10
STAT3 contributes to NK cell recognition by modulating expression of NKG2D ligands in adriamycin-resistant K562/AO2 cells.信号转导和转录激活因子3（STAT3）通过调节阿霉素耐药K562/AO2细胞中NKG2D配体的表达来促进自然杀伤（NK）细胞的识别。
Int J Hematol. 2015 Nov;102(5):536-43. doi: 10.1007/s12185-015-1860-7. Epub 2015 Sep 19.