Tajiri Eri, Yoshimura Eiichi, Hatamoto Yoichi, Shiratsuchi Hideki, Tanaka Shigeho, Shimoda Seiya
Graduate School of Environmental and Symbiotic Sciences, Prefectural University of Kumamoto, 3-1-100 Tsukide, Higashi-ku, Kumamoto 862-8502, Japan.
Faculty of Environmental and Symbiotic Sciences, Prefectural University of Kumamoto, 3-1-100 Tsukide, Higashi-ku, Kumamoto 862-8502, Japan.
Behav Sci (Basel). 2020 Feb 1;10(2):47. doi: 10.3390/bs10020047.
This study aimed to examine the effect of acute sleep curtailment on sweet taste preference, appetite and food intake, and the correlation between food intake and sweet taste preference or active ghrelin using a randomized crossover design (5 h sleep curtailment vs. 8 h control). Twenty-four participants (11 men) aged 21.4 ± 1.0 years, with BMI 19.8 ± 1.7 kg/m, who habitually slept 5 h/night or more experienced interventions lasting three consecutive nights. Participants came into the laboratory for testing on day 4. Fasting blood tests were conducted at 8:00 a.m. to measure active ghrelin and leptin levels. Sweet taste preference was assessed by presenting five different concentration sucrose solutions at 9:00 a.m. intake at breakfast was assessed for 30 min from 9:30 a.m. Sweet taste preference was higher following sleep curtailment than control. Active ghrelin was likewise higher following sleep curtailment than control. Leptin did not differ between conditions. Energy intake was higher following sleep curtailment than control, being derived primarily from carbohydrates. However, sweet taste preference and active ghrelin did not correlate with energy intake. These results suggest that acute consecutive sleep curtailment increases sweet taste preference, active ghrelin, and energy intake in healthy young adults.
本研究旨在采用随机交叉设计（5小时睡眠减少组与8小时对照组），探讨急性睡眠减少对甜味偏好、食欲和食物摄入量的影响，以及食物摄入量与甜味偏好或活性胃饥饿素之间的相关性。24名参与者（11名男性），年龄21.4±1.0岁，体重指数为19.8±1.7kg/m²，习惯性每晚睡眠5小时或更长时间，连续三个晚上接受干预。第4天参与者进入实验室进行测试。上午8点进行空腹血液检测，以测量活性胃饥饿素和瘦素水平。上午9点通过提供五种不同浓度的蔗糖溶液来评估甜味偏好。从上午9点30分开始评估30分钟的早餐摄入量。睡眠减少组的甜味偏好高于对照组。睡眠减少组的活性胃饥饿素同样高于对照组。不同条件下瘦素无差异。睡眠减少组的能量摄入量高于对照组，主要来源于碳水化合物。然而，甜味偏好和活性胃饥饿素与能量摄入量无关。这些结果表明，急性连续睡眠减少会增加健康年轻成年人的甜味偏好、活性胃饥饿素和能量摄入量。
