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自发性颅内低压综合征中的脊髓脑脊液漏:一项鞘内钆增强磁共振脊髓造影研究

Spinal Cerebrospinal Fluid Leakage in Spontaneous Intracranial Hypotension: An Intrathecal Gadolinium Enhanced MR-Myelography Study.

作者信息

Cebeci Hakan, Bilgin Cem, Candan Selman, Demir Aylin Bican, Hakyemez Bahattin

机构信息

Department of Radiology, Selcuk University, Faculty of Medicine, Konya, TR.

Department of Radiology, Bursa Uludag University, Faculty of Medicine, Bursa, TR.

出版信息

J Belg Soc Radiol. 2020 Jan 30;104(1):6. doi: 10.5334/jbsr.1877.

DOI:10.5334/jbsr.1877
PMID:32025622
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6993594/
Abstract

OBJECTIVES

In the present study, the authors presented the intrathecal gadolinium enhanced MR-myelography findings of patients with spontaneous intracranial hypotension.

MATERIALS AND METHODS

Intrathecal gadolinium enhanced MR-myelography (Gd-MR-myelography) examinations between October 2012 and September 2018 in patients having clinical and radiological findings of spontaneous intracranial hypotension were evaluated retrospectively. Sites and types of contrast leakages in 20 patients who met inclusion criteria were reviewed. All patients had undergone T1-fat suppressed sagittal images of cervical, thoracic and lumbar region after the off label intrathecal injection of 1 ml gadolinium-based contrast agent.

RESULTS

Patients (18 female, 2 male) are aged between 23 and 62 years-old (mean age: 41.1). Cerebrospinal fluid (CSF) leakages were cervical in 6 patients, thoracic in 5 patients, lumbar in 5 patients. One patient had leakage in multiple levels on both cervical and thoracic region and another patient on both cervical-thoracic and lumbar regions. No patients had adverse effects related to intrathecal injection of gadolinium.

CONCLUSIONS

Gd-MR-myelography is effective imaging modality to reveal spinal CSF leakages in patients with spontaneous intracranial hypotension.

摘要

目的

在本研究中,作者展示了自发性颅内低压患者的鞘内钆增强磁共振脊髓造影结果。

材料与方法

回顾性评估2012年10月至2018年9月期间有自发性颅内低压临床和影像学表现的患者的鞘内钆增强磁共振脊髓造影(Gd-MR-脊髓造影)检查。对符合纳入标准的20例患者的造影剂渗漏部位和类型进行了回顾。所有患者在鞘内非标签注射1 ml钆基造影剂后均接受了颈椎、胸椎和腰椎区域的T1脂肪抑制矢状位图像检查。

结果

患者(18例女性,2例男性)年龄在23至62岁之间(平均年龄:41.1岁)。脑脊液(CSF)漏出部位为颈椎6例,胸椎5例,腰椎5例。1例患者在颈椎和胸椎区域均有多处漏出,另1例患者在颈胸和腰椎区域均有漏出。没有患者出现与鞘内注射钆相关的不良反应。

结论

Gd-MR-脊髓造影是揭示自发性颅内低压患者脊髓CSF漏出的有效成像方式。

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Invest Radiol. 2018 Sep;53(9):535-540. doi: 10.1097/RLI.0000000000000472.
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Update on the Diagnosis and Treatment of Spontaneous Intracranial Hypotension.自发性颅内低压的诊断与治疗进展
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