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遗传性血管性水肿患者行腹壁提升腹腔镜胆囊切除术时的成功麻醉管理

Successful anesthetic management during abdominal wall-lifting laparoscopic cholecystectomy in a patient with hereditary angioedema.

作者信息

Fujii Masashi, Higashiguchi Takayuki, Shime Nobuaki, Kawabata Yasuyo

机构信息

Department of Anaesthesia, Nagahama Red Cross Hospital, 14-7 Miyamae-cho, Nagahama, Shiga, 526-8585, Japan.

Department of Surgery, Nagahama Red Cross Hospital, Nagahama, Shiga, Japan.

出版信息

JA Clin Rep. 2018 May 9;4(1):38. doi: 10.1186/s40981-018-0174-1.

Abstract

BACKGROUND

Hereditary angioedema is a rare genetic disorder resulting from an inherited deficiency or dysfunction of the C1-esterase inhibitor. In the anesthetic management of such patients, special caution should be exercised while attempting tracheal intubation because it may cause mucosal edema in the upper airway.

CASE PRESENTATION

A 52-year-old female with hereditary angioedema was scheduled for laparoscopic cholecystectomy. C1-esterase inhibitor, Danazol, tranexamic acid, and prednisolone were administered on the day of surgery. An epidural catheter was inserted through the intervertebral space at T9/10, and spinal anesthesia was instilled via the L3/4 intervertebral space. A single-hole, Nishii-type lifting laparoscopic surgery, without pneumoperitoneum (i.e., gasless) was completed uneventfully.

CONCLUSION

This report described the successful management of a patient with hereditary angioedema who underwent laparoscopic cholecystectomy using spinal-epidural anesthesia without tracheal intubation and lift type laparoscopic surgery. This approach to anesthetic management could be indicated in cases with a similar presentation.

摘要

背景

遗传性血管性水肿是一种罕见的遗传性疾病,由C1酯酶抑制剂的遗传性缺乏或功能障碍引起。在此类患者的麻醉管理中,气管插管时应格外小心,因为这可能导致上呼吸道黏膜水肿。

病例报告

一名52岁患有遗传性血管性水肿的女性计划接受腹腔镜胆囊切除术。手术当天给予了C1酯酶抑制剂、达那唑、氨甲环酸和泼尼松龙。通过T9/10椎间隙插入硬膜外导管,并通过L3/4椎间隙注入脊髓麻醉。顺利完成了单孔、西井式提拉腹腔镜手术,无气腹(即无气)。

结论

本报告描述了一名患有遗传性血管性水肿的患者成功接受了腹腔镜胆囊切除术,采用脊髓-硬膜外麻醉,未进行气管插管和提拉式腹腔镜手术。这种麻醉管理方法可用于类似病例。

相似文献

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Abdominal lift for laparoscopic cholecystectomy.用于腹腔镜胆囊切除术的腹部提升术。
Cochrane Database Syst Rev. 2012 May 16(5):CD006574. doi: 10.1002/14651858.CD006574.pub3.
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Hormonally exacerbated hereditary angioedema.激素加重型遗传性血管性水肿
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本文引用的文献

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WAO Guideline for the Management of Hereditary Angioedema.WAO 遗传性血管性水肿管理指南。
World Allergy Organ J. 2012 Dec;5(12):182-99. doi: 10.1097/WOX.0b013e318279affa.

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