Suppr超能文献

[医院及私人诊所中急性中耳炎的细菌学研究]

[Bacteriologic study of acute otitis media in hospitals and private practice].

作者信息

François M, Bingen E, Margo J N, Sichel J Y, Lambert N, Narcy P

机构信息

Service d'Otorhinolaryngologie, Hôpital Bretonneau, Paris.

出版信息

Arch Fr Pediatr. 1988 Aug-Sep;45(7):471-6.

PMID:3202671
Abstract

The authors report the results of the study of 435 bacteriological samples taken in children presenting with acute otitis media, in the out-patient department of ENT at the hospital Bretonneau (Paris) and in Valognes (Manche) from October 1981 to September 1987. Three bacterial organisms prevailed: Haemophilus (37 and 22% respectively), S. pneumoniae (25 and 7%) and Staphylococcus (16 and 17%). Pseudomonas was fairly frequent in cases with otorrhea, even when recent. Comparison with other studies shows the clear progression of the incidence of Haemophilus in acute otitis media. The percentage of the strains secreting a beta-lactamase was 17% whether the children live in the country or in town. The frequency of S. pneumoniae was independent of age but was clearly lower in cases with prolonged or relapsing otitis. According to these results, the authors discuss the therapeutic strategy for acute otitis media. Amoxicillin still remains the antibiotic of choice. In case of persisting or relapsing otitis, the bacteriological examination will allow choosing the best adapted antibiotic: first generation cephalosporin, clavulanic acid and amoxicillin or trimethoprime and sulfamethoxazole.

摘要

作者报告了1981年10月至1987年9月期间在布雷托诺医院(巴黎)和瓦洛涅(芒什省)耳鼻喉科门诊对435例患有急性中耳炎的儿童进行细菌学样本研究的结果。三种主要细菌为:嗜血杆菌(分别占37%和22%)、肺炎链球菌(25%和7%)和葡萄球菌(16%和17%)。即使是近期发生的耳漏病例,假单胞菌也相当常见。与其他研究的比较显示,急性中耳炎中嗜血杆菌的发病率有明显上升。无论儿童生活在农村还是城市,分泌β-内酰胺酶的菌株比例均为17%。肺炎链球菌的感染频率与年龄无关,但在中耳炎病程延长或复发的病例中明显较低。根据这些结果,作者讨论了急性中耳炎的治疗策略。阿莫西林仍然是首选抗生素。对于持续性或复发性中耳炎病例,细菌学检查将有助于选择最适合的抗生素:第一代头孢菌素、克拉维酸和阿莫西林或甲氧苄啶和磺胺甲恶唑。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验