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断臂再植的长期疗效。

Long-Term Outcomes of Arm Replantation.

机构信息

Joseph M. Still Burn and Reconstruction Center, Miami, FL.

From the Joseph M. Still Burn and Reconstruction Center, Jackson, MS.

出版信息

Ann Plast Surg. 2020 Mar;84(3S Suppl 2):S151-S157. doi: 10.1097/SAP.0000000000002283.

Abstract

BACKGROUND

Advances in microsurgery have improved the survival rate of arm replantation. However, the functional outcome of the replanted arms remains unpredictable. The authors performed a systematic review to evaluate the long-term outcome of arm replantation and the secondary reconstructive procedures after replantation.

METHODS

All available English literature in the PubMed, Embase, and CENTRAL databases was searched for articles reporting functional outcome of successful arm replantation with follow-up period more than 1 yr. Clinical data were extracted including study characteristics, patient demographic information, functional outcome, and the numbers, types, and timing of secondary surgery. Among these, factors identified to influence overall outcome were reviewed and analyzed.

RESULTS

Twenty-nine studies representing 79 arm replantations met the inclusion criteria. A total of 111 secondary procedures were recorded in 23 studies. The average number of secondary surgical procedures was 2.6 per patient. The most common procedures were nerve repair (23.4%), followed by functioning muscle transfer (19.8%), tendon transfer (17.1%), wound coverage (11.7%), contracture release (10.8%), bone repair (9.9%), arthrodesis (5.4%), and others (1.8%). Procedures involving wound coverage and nerve repair were mainly conducted in the early stage within 4 mos after replantation, whereas functioning muscle transfer, tendon transfer, and arthrodesis were mostly performed after 1 yr postoperatively. The satisfied (Chen I and II) functional outcome was achieved in 49.4% patients. The level of amputation and the type of injury have significant impact on final outcomes, whereas patients' age and timing of nerve repair do not. Patients with amputation at the distal third of the arms had a better outcome than those at the proximal and middle third of the arms (P < 0.05), and patients injured by sharp-cut recovered better than those by crush and avulsion (P < 0.05).

CONCLUSIONS

Optimal outcomes could be achieved in nearly half of patients with arm replantation, although multiple secondary surgical interventions and long periods of recovery are often required.

摘要

背景

显微外科技术的进步提高了断肢再植的成活率。然而,再植手臂的功能预后仍然难以预测。作者进行了一项系统评价,以评估断肢再植的长期预后以及再植后的二次重建手术。

方法

在 PubMed、Embase 和 CENTRAL 数据库中检索所有关于成功的断肢再植且随访时间超过 1 年的功能预后的英文文献。提取包括研究特征、患者人口统计学信息、功能预后以及二次手术的数量、类型和时间等临床数据。对影响总体预后的因素进行了回顾和分析。

结果

符合纳入标准的研究有 29 项,共 79 例断肢再植。在 23 项研究中记录了 111 例二次手术。平均每位患者接受 2.6 次二次手术。最常见的手术是神经修复(23.4%),其次是功能性肌肉转移(19.8%)、肌腱转移(17.1%)、创面覆盖(11.7%)、挛缩松解(10.8%)、骨修复(9.9%)、关节融合术(5.4%)和其他手术(1.8%)。创面覆盖和神经修复手术主要在再植后 4 个月内的早期进行,而功能性肌肉转移、肌腱转移和关节融合术主要在术后 1 年进行。49.4%的患者获得了满意(Chen I 和 II)的功能预后。截肢水平和损伤类型对最终结果有显著影响,而患者的年龄和神经修复的时间没有影响。手臂远端截肢的患者比近端和中段截肢的患者预后更好(P < 0.05),切割伤患者比挤压伤和撕脱伤患者恢复更好(P < 0.05)。

结论

虽然需要多次二次手术干预和长时间的恢复,但近一半的断肢再植患者可以获得最佳的结果。

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