Department of Pharmacology and Therapeutics, Seth GS Medical College and KEM Hospital, Mumbai, Maharashtra, India.
Indian J Pharmacol. 2019 Nov-Dec;51(6):400-406. doi: 10.4103/ijp.IJP_297_18. Epub 2020 Jan 16.
The objective of the study is to evaluate the perception of postgraduate pharmacology students toward computer-simulated method (CSM) in comparison to the prevalent isolated live tissue-based bioassay method.
A questionnaire-based survey was conducted in 30 postgraduate pharmacology students who had used the animal simulation software and had completed at least five isolated tissue experiments. Students' opinions on the usage, logistics, advantages, disadvantages, and usefulness of CSM compared to live animal experiments (LAE) were analyzed.
Four tissues were used for LAE, whereas with CSM, students could perform experiments using 11 different tissues. Of the total nine bioassay methods, students had performed six assay methods using both LAE and CSM. Majority of the students (23/30) agreed that CSM reduces anxiety, technical errors and is less time consuming when used before LAE. Most of the students agreed that CSM can be used for difficult, lengthy experiments (19/30), and for UG/PG teaching (19/30). However, opinions regarding replacing LAE with CSM in PG teaching were divided (agree: 7, neutral: 12, and disagree: 12).
CSM should be integrated alongside LAE to complement, reinforce, and enhance learning from other techniques.
本研究旨在评估研究生药理学学生对计算机模拟方法（CSM）的认知，与流行的独立活体组织生物测定方法相比。
对 30 名使用过动物模拟软件并完成至少 5 个离体组织实验的研究生药理学学生进行了基于问卷调查的研究。分析了学生对 CSM 相对于活体动物实验（LAE）的使用、物流、优缺点和实用性的看法。
LAE 中使用了四种组织，而使用 CSM，学生可以使用 11 种不同的组织进行实验。在总共 9 种生物测定方法中，学生使用 LAE 和 CSM 完成了六种测定方法。大多数学生（23/30）同意 CSM 在 LAE 之前使用可以减轻焦虑、技术错误并减少时间消耗。大多数学生同意 CSM 可用于困难、冗长的实验（19/30）和 UG/PG 教学（19/30）。然而，关于在 PG 教学中用 CSM 代替 LAE 的意见存在分歧（同意：7，中立：12，不同意：12）。
CSM 应与 LAE 结合使用，以补充、加强和增强其他技术的学习效果。
