Anari Jason B, Flynn John M, Cahill Patrick J, Vitale Michael G, Smith John T, Gomez Jaime A, Garg Sumeet, Baldwin Keith D
The Children's Hospital of Philadelphia, 3400 Civic Center Boulevard, Philadelphia, PA, 19104, USA.
New York-Presbyterian/Morgan Stanley Children's Hospital, 3959 Broadway Rm 800N, New York, NY, 10032, USA.
Spine Deform. 2020 Apr;8(2):295-302. doi: 10.1007/s43390-019-00024-0. Epub 2020 Feb 6.
Retrospective analysis of a prospectively collected multicenter database.
Our goal was to study unplanned return to the OR (UPROR, a postoperative complication that could not be treated without an additional anesthetic) as a function of C-EOS diagnosis and implant type. Growing concerns over the impact of multiple anesthetic events on the young brain have focused attention on limiting UPROR in early onset scoliosis (EOS).
We studied all patients with a diagnosis of EOS who had surgical implantation of growing instrumentation from October 4, 2010, to September 27, 2015, with a minimum 2-year follow-up. Among the complications requiring surgical treatment (revision for implant or anchor failure, infection, or implant removal), we analyzed all UPROR events-those that required a separate anesthetic (could not be treated as part of a planned surgical lengthening) within the first 2 years after initial implantation. UPROR was analyzed by diagnosis, deformity type, and implant strategy using the C-EOS classification.
A total of 369 patients met inclusion criteria. Eighty-five of the 369 (23%) required unplanned trips to the operating room for various reasons. The C-EOS group at highest risk of an unplanned trip to the operating room is the hyperkyphotic neuromuscular (M3+, 14/85) cohort, followed closely by the congenital (C3N, 9/85) and neuromuscular (M3N, 8/85) groups with normal sagittal profiles and Cobb angles between 50° and 90°. Implant strategy was significantly related to risk of UPROR (p = .009; Table 1), with traditional implants (vertically expandable prosthetic titanium rib/traditional growing rod) being less likely to have an UPROR event.
Growing instrumentation to treat EOS, when considered comprehensively, results in a true unplanned reoperation rate within 2 years of implantation of 23% (85/369). UPROR events are more common with certain C-EOS groups (hyperkyphotic neuromuscular deformities) and implant strategies. Families should be counseled that unplanned anesthetics are common with any implant strategy available today.
Level III, therapeutic.
对前瞻性收集的多中心数据库进行回顾性分析。
我们的目标是研究计划外重返手术室(UPROR,一种不进行额外麻醉就无法治疗的术后并发症)与C-EOS诊断和植入物类型之间的关系。对多次麻醉事件对幼龄大脑影响的日益关注,已将注意力集中在限制早发性脊柱侧弯(EOS)患者的UPROR上。
我们研究了2010年10月4日至2015年9月27日期间所有诊断为EOS且接受了生长棒植入手术的患者,并进行了至少2年的随访。在需要手术治疗的并发症(因植入物或锚钉失败、感染或取出植入物而进行翻修)中,我们分析了所有UPROR事件,即在初次植入后的前2年内需要单独麻醉(不能作为计划性手术延长的一部分进行治疗)的事件。使用C-EOS分类法,按诊断、畸形类型和植入策略对UPROR进行分析。
共有369例患者符合纳入标准。369例患者中有85例(23%)因各种原因需要计划外前往手术室。计划外前往手术室风险最高的C-EOS组是后凸型神经肌肉型(M3+,14/85)队列,其次是矢状面轮廓正常且Cobb角在50°至90°之间的先天性(C3N,9/85)和神经肌肉型(M3N,8/85)组。植入策略与UPROR风险显著相关(p = 0.009;表1),传统植入物(垂直可扩展人工钛肋/传统生长棒)发生UPROR事件的可能性较小。
综合考虑,用于治疗EOS的生长棒植入在植入后2年内的真正计划外再次手术率为23%(85/369)。某些C-EOS组(后凸型神经肌肉畸形)和植入策略的UPROR事件更为常见。应告知家属,使用目前任何一种植入策略,计划外麻醉都很常见。
三级,治疗性。