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透视引导下膝神经脉冲射频治疗慢性膝关节疼痛

Fluoroscopy-guided genicular nerves pulsed radiofrequency for chronic knee pain treatment.

作者信息

Arıcan Şule, Hacibeyoglu Gülçin, Akkoyun Sert Özlem, Tuncer Uzun Sema, Reisli Ruhiye

机构信息

Department of Anaesthesiology and Reanimation, Necmettin Erbakan University Faculty of Medicine, Konya, Turkey.

Department of Physical Therapy and Rehabilitation, Karatay University, Konya, Turkey.

出版信息

Agri. 2020 Jan;32(1):38-43. doi: 10.14744/agri.2019.16779.

Abstract

OBJECTIVES

The primary objective of this study was to investigate the effects of Pulsed RF application in the genicular nerve on pain and function in patients with osteoarthritis (OA) and its side effects.

METHODS

This study was conducted between February 2018 and June 2018. Patients who were previously administered diagnostic blocks were evaluated a day later; a drop of at least 50% in numeric pain scores was considered a positive response, and these patients were included in the Pulsed RF neurotomy procedures. Radiofrequency (RF) cannula was advanced towards targeted nerves under the guidance of fluoroscopy. RF lesions were created by applying Pulsed RF treatment to the three genicular nerves three times with five minutes intervals at 42 °C using NT1000 RF Generator. Following the Pulsed RF application, 2 mL 0.5% bupivacaine was injected into each genicular nerve as an anesthetic agent. VAS, pain DETECT scores, WOMAC scores were evaluated preoperative baseline and postprocedure weeks 1, 4, and 12. Patient Global Impression of Change (PGIC) score was evaluated postprocedure weeks 12.

RESULTS

This study included 20 patients who were administered genicular nerve Pulsed RF. The mean age was 55.2±3.24 years, and F/M ratio was 12/8. Compared to the pre-procedure period, patients' pain and function evaluation, WOMAC and VAS values decreased by approximately 50% at the end of the 12th week. No side effect was observed in any patients.

CONCLUSION

Our findings suggest that Pulsed RF neurotomy of the genicular nerves is an efficient and safe treatment method for patients with chronic knee osteoarthritis.

摘要

目的

本研究的主要目的是探讨膝神经脉冲射频治疗对骨关节炎(OA)患者疼痛和功能的影响及其副作用。

方法

本研究于2018年2月至2018年6月进行。曾接受诊断性阻滞的患者在一天后进行评估;数字疼痛评分至少下降50%被视为阳性反应,这些患者被纳入脉冲射频神经切断术。在荧光透视引导下,将射频(RF)套管针推进至目标神经。使用NT1000射频发生器,在42℃下,以5分钟的间隔对三条膝神经进行三次脉冲射频治疗,形成射频损伤。脉冲射频治疗后,向每条膝神经注射2 mL 0.5%布比卡因作为麻醉剂。在术前基线以及术后第1、4和12周评估视觉模拟评分(VAS)、疼痛DETECT评分、西安大略和麦克马斯特大学骨关节炎指数(WOMAC)评分。在术后第12周评估患者整体变化印象(PGIC)评分。

结果

本研究纳入了20例接受膝神经脉冲射频治疗的患者。平均年龄为55.2±3.24岁,男/女比例为12/8。与术前相比,患者的疼痛和功能评估、WOMAC和VAS值在第12周结束时下降了约50%。未观察到任何患者出现副作用。

结论

我们的研究结果表明,膝神经脉冲射频神经切断术是治疗慢性膝骨关节炎患者的一种有效且安全的治疗方法。

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