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安罗替尼治疗老年复发性晚期小细胞肺癌患者

Anlotinib in treatment of an elderly patient with recurrent advanced SCLC.

作者信息

Zhang Ying, Jia Beili, Li Jing, Xu Xiaomei

机构信息

Department of Internal Medicine, Municipal Hospital, Qingdao, Shandong, People's Republic of China.

Department of Medical Oncology, Municipal Hospital, Qingdao, Shandong, People's Republic of China.

出版信息

Tumori. 2020 Dec;106(6):NP36-NP40. doi: 10.1177/0300891619900673. Epub 2020 Feb 7.

DOI:10.1177/0300891619900673
PMID:32031060
Abstract

INTRODUCTION

An elderly patient with advanced small cell lung cancer who had a history of smoking and who had previously had tuberculosis and chronic kidney disease relapsed after classical treatment with etoposide combined with carboplatin.

METHODS

The patient was given chemotherapy again, with albumin-bound paclitaxel, etoposide capsules, apatinib, and other treatment. The last medication was apatinib.

RESULTS

After treatment with anlotinib, the patient has survived for 15 months with good quality of life.

CONCLUSION

This is the first report on the precise efficacy of anlotinib in the treatment of advanced small cell lung cancer. Anlotinib is an important option for patients with small cell lung cancer.

摘要

引言

一名老年晚期小细胞肺癌患者,有吸烟史,既往患过结核病和慢性肾脏病,在接受依托泊苷联合卡铂的经典治疗后复发。

方法

该患者再次接受化疗,使用了白蛋白结合型紫杉醇、依托泊苷胶囊、阿帕替尼等治疗。最后使用的药物是阿帕替尼。

结果

使用安罗替尼治疗后,患者已存活15个月,生活质量良好。

结论

这是关于安罗替尼治疗晚期小细胞肺癌确切疗效的首篇报道。安罗替尼是小细胞肺癌患者的重要选择。

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1
Anlotinib in treatment of an elderly patient with recurrent advanced SCLC.安罗替尼治疗老年复发性晚期小细胞肺癌患者
Tumori. 2020 Dec;106(6):NP36-NP40. doi: 10.1177/0300891619900673. Epub 2020 Feb 7.
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Anlotinib-containing regimen for advanced small-cell lung cancer: A protocol of meta-analysis.含安罗替尼方案治疗晚期小细胞肺癌的荟萃分析方案。
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Response to first-line treatment predicts progression-free survival benefit of small-cell lung cancer patients treated with anlotinib.一线治疗应答可预测安罗替尼治疗小细胞肺癌患者的无进展生存期获益。
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The Efficacy and Safety of Anlotinib Alone and in Combination with Other Drugs in Advanced Lung Cancer: A Retrospective Cohort Study.安罗替尼单药及联合其他药物治疗晚期肺癌的疗效和安全性:一项回顾性队列研究。
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China National Medical Products Administration approval summary: anlotinib for the treatment of advanced non-small cell lung cancer after two lines of chemotherapy.中国国家药品监督管理局批准概要:安罗替尼用于二线化疗后治疗晚期非小细胞肺癌。
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Safety and efficacy of ICI plus anlotinib vs. anlotinib alone as third-line treatment in extensive-stage small cell lung cancer: a retrospective study.ICI 联合安罗替尼对比安罗替尼单药作为广泛期小细胞肺癌三线治疗的安全性和有效性:一项回顾性研究。
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Comparison of the efficacy and safety of anlotinib monotherapy or anlotinib plus immune checkpoint inhibitor for advanced small cell lung cancer with brain metastases.安罗替尼单药或联合免疫检查点抑制剂治疗伴有脑转移的晚期小细胞肺癌的疗效和安全性比较。
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Efficacy and Safety of Anlotinib in EGFR-Positive Patients with Advanced Lung Adenocarcinoma Compared with Chemotherapy: A Retrospective Study.安罗替尼对比化疗用于 EGFR 阳性晚期肺腺癌患者的疗效和安全性:一项回顾性研究。
Technol Cancer Res Treat. 2024 Jan-Dec;23:15330338241279111. doi: 10.1177/15330338241279111.

引用本文的文献

1
Safety of Anlotinib Capsules Combined with PD-1 Inhibitor Camrelizumab in the Third-Line Treatment of Advanced Non-Small-Cell Lung Cancer and Their Effect on Serum Tumor Markers.安罗替尼胶囊联合 PD-1 抑制剂卡瑞利珠单抗三线治疗晚期非小细胞肺癌的安全性及其对血清肿瘤标志物的影响。
J Healthc Eng. 2021 Dec 15;2021:2338800. doi: 10.1155/2021/2338800. eCollection 2021.
2
Response to first-line treatment predicts progression-free survival benefit of small-cell lung cancer patients treated with anlotinib.一线治疗应答可预测安罗替尼治疗小细胞肺癌患者的无进展生存期获益。
Cancer Med. 2021 Jun;10(12):3896-3904. doi: 10.1002/cam4.3941. Epub 2021 May 6.