Department of Otolaryngology, Head & Neck Surgery, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China.
Acta Otolaryngol. 2020 Apr;140(4):258-261. doi: 10.1080/00016489.2019.1708458. Epub 2020 Feb 7.
Endolymphatic sac decompression surgery (ESDS) is commonly used for intractable Meniere's disease, but its effect remains controversial because of the low rate of vertigo control. In the present study, we examined ESDS combined with posterior tympanotomy with local steroids as a new therapeutic strategy for intractable Meniere's disease. This retrospective study enrolled 19 patients with Meniere's disease using ESDS combined with posterior tympanotomy with local steroids between 2015 and 2018. Postoperatively we recorded and evaluated changes in vertigo attack frequency and hearing level. Vertigo episodes decreased from 3.6 ± 3.2 times preoperatively to 0.2 ± 0.5 times postoperatively, with 89.5% complete vertigo control rate. Mean PTA decreased from 40.5 ± 21.3 dB to 39.5 ± 17.5 dB postoperatively, with 21.1% improvement rate. The present findings suggest that ESDS combined with posterior tympanotomy with local steroids could improve clinical results of hearing as well as vertigo control for intractable Meniere's disease.
内淋巴囊减压术（ESDS）常用于治疗难治性梅尼埃病，但由于眩晕控制率较低，其疗效仍存在争议。在本研究中，我们研究了 ESDS 联合局部类固醇后鼓室切开术作为治疗难治性梅尼埃病的新治疗策略。本回顾性研究纳入了 2015 年至 2018 年间接受 ESDS 联合局部类固醇后鼓室切开术的 19 例梅尼埃病患者。术后记录并评估了眩晕发作频率和听力水平的变化。眩晕发作从术前的 3.6±3.2 次减少到术后的 0.2±0.5 次，完全控制眩晕率为 89.5%。平均纯音听阈从术前的 40.5±21.3dB 降低到术后的 39.5±17.5dB，听力改善率为 21.1%。本研究结果表明，ESDS 联合局部类固醇后鼓室切开术可改善难治性梅尼埃病的听力及眩晕控制的临床效果。
