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老年患者在乳房缩小成形术中发生深静脉血栓形成和肺栓塞的风险增加:对2005年至2017年国家外科质量改进项目数据库中25909例病例中的1897例老年患者的分析。

Geriatric Patients Carry Increased Risk for Deep Venous Thrombosis and Pulmonary Embolism in Reduction Mammaplasty: An Analysis of 1897 Geriatric Patients Among 25,909 Cases From 2005 to 2017 National Surgical Quality Improvement Project Databases.

作者信息

Davé Dattesh R, Arora Aman, Zeiderman Matthew R, Wong Michael S

机构信息

From the Division of Plastic and Reconstructive Surgery, University of California School of Medicine, Davis, CA.

出版信息

Ann Plast Surg. 2020 May;84(5S Suppl 4):S264-S267. doi: 10.1097/SAP.0000000000002242.

Abstract

INTRODUCTION

Reduction mammaplasty is one of the most common plastic surgery procedures performed. No study has evaluated whether geriatric patients are at greater risk for developing postoperative complications relative to nongeriatric patients.

METHODS

The American College of Surgeons National Surgical Quality Improvement Project (NSQIP) database was reviewed for reduction mammaplasty procedures from 2005 to 2017. Hypothesis testing for demographics, comorbidities, and postoperative complications between geriatric and nongeriatric patients was performed. Statistically significant differences were then evaluated with multivariate logistic regression analysis.

RESULTS

A total of 25,909 reduction mammaplasties were collected by NSQIP from 2005 to 2017, with 1897 patients older than 64 years (8% of all cases). The average age for geriatric breast reduction patients was 69 years versus 41.5 years for nongeriatric patients. Rates of comorbidities including diabetes, smoking status, dyspnea status, and hypertension medication were statistically different between the groups. Rates of deep venous thrombosis (DVT) and pulmonary embolism (PE) were significantly higher in geriatric versus nongeriatric patients, respectively (0.32 vs 0.06, P < 0.001 and 0.37 vs 0.09, P < 0.001). Multivariate analysis demonstrated geriatric patients had a 4.2 and 3.9 times higher risk of developing a DVT and PE than nongeriatric patients (C.I. 1.5-11.6, P = 0.006 and C.I. 1.6-9.8, P = 0.004).

DISCUSSION

This study represents the largest evaluation of geriatric reduction mammaplasties in the United States. Although rare, geriatric age confers a 4 times increased risk for developing DVT and PE relative to nongeriatric patients all while adjusting for preoperative risk factors in reduction mammaplasty. Plastic surgeons should consider counseling their geriatric patients regarding these increased risks.

摘要

引言

缩乳术是最常见的整形手术之一。尚无研究评估老年患者相对于非老年患者发生术后并发症的风险是否更高。

方法

回顾美国外科医师学会国家外科质量改进项目(NSQIP)数据库中2005年至2017年的缩乳术病例。对老年和非老年患者的人口统计学、合并症及术后并发症进行假设检验。然后采用多因素逻辑回归分析评估具有统计学意义的差异。

结果

NSQIP在2005年至2017年共收集了25909例缩乳术病例,其中1897例患者年龄超过64岁(占所有病例的8%)。老年缩乳患者的平均年龄为69岁,而非老年患者为41.5岁。两组之间的合并症发生率,包括糖尿病、吸烟状况、呼吸困难状况及高血压用药情况,在统计学上存在差异。老年患者深静脉血栓形成(DVT)和肺栓塞(PE)的发生率分别显著高于非老年患者(0.32对0.06,P<0.001;0.37对0.09,P<0.001)。多因素分析表明,老年患者发生DVT和PE的风险分别比非老年患者高4.2倍和3.9倍(置信区间1.5 - 11.6,P = 0.006;置信区间1.6 - 9.8,P = 0.004)。

讨论

本研究是美国对老年缩乳术规模最大的评估。尽管罕见,但在调整缩乳术术前风险因素后,老年患者发生DVT和PE的风险相对于非老年患者增加了4倍。整形外科医生应考虑就这些增加的风险向老年患者提供咨询。

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