Department of Large Animal Internal Medicine, Faculty of Veterinary Medicine, Ghent University, Equine cardioteam, Ghent University, Merelbeke, Belgium.
Department of Pathology, Bacteriology and Poultry Diseases, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium.
J Vet Intern Med. 2020 Mar;34(2):893-901. doi: 10.1111/jvim.15705. Epub 2020 Feb 7.
Aortic rupture is more common in Friesians compared to Warmbloods, which might be related to differences in arterial wall composition and, as such, arterial wall stiffness (AWS). Currently, nothing is known about differences in AWS between these breeds.
Comparison of AWS parameters and noninvasive blood pressure between Friesians and Warmbloods.
One hundred one healthy Friesians and 101 age-matched healthy Warmbloods.
Two-dimensional and pulsed-wave Doppler ultrasound examination was performed of the aorta, common carotid artery, and external iliac artery to define local and regional AWS parameters. Regional aortic AWS was estimated using aortic-to-external iliac artery pulse wave velocity (PWV ) and carotid-to-external iliac artery pulse wave velocity (PWV ). Noninvasive blood pressure and heart rate were recorded simultaneously.
Systolic, diastolic, and mean arterial blood pressure and pulse pressure were significantly higher in Friesians compared to Warmbloods. No significant difference in heart rate was found. Most local AWS parameters (diameter change, compliance coefficient, distensibility coefficient) were significantly lower in Friesians compared to Warmbloods, indicating a stiffer aorta in Friesians. This difference could be confirmed by the regional stiffness parameters. A higher PWV and PWV was found in Friesians. For the cranial and caudal common carotid artery and external iliac artery, most local AWS parameters were not significantly different.
Results indicate that aortic AWS differs between Friesian and Warmblood horses. Friesians seem to have a stiffer aorta, which might be related to the higher incidence of aortic rupture in Friesians.
与温血马相比，弗里西亚马更容易发生主动脉破裂，这可能与动脉壁成分的差异有关，因此与动脉壁僵硬度（AWS）有关。目前，尚不清楚这两个品种之间 AWS 的差异。
比较弗里西亚马和温血马的 AWS 参数和无创血压。
101 匹健康的弗里西亚马和 101 匹年龄匹配的健康温血马。
对主动脉、颈总动脉和髂外动脉进行二维和脉冲波多普勒超声检查，以确定局部和区域 AWS 参数。使用主动脉-髂外动脉脉搏波速度（PWV）和颈动脉-髂外动脉脉搏波速度（PWV）估计区域性主动脉 AWS。同时记录无创血压和心率。
与温血马相比，弗里西亚马的收缩压、舒张压和平均动脉压以及脉压均显著升高。心率无显著差异。与温血马相比，弗里西亚马的大多数局部 AWS 参数（直径变化、顺应性系数、伸展性系数）均显著降低，表明弗里西亚马的主动脉更僵硬。这一差异可以通过区域性僵硬度参数得到证实。弗里西亚马的 PWV 和 PWV 更高。对于颅侧和尾侧颈总动脉和髂外动脉，大多数局部 AWS 参数无显著差异。
结果表明，弗里西亚马和温血马的主动脉 AWS 不同。弗里西亚马的主动脉似乎更僵硬，这可能与弗里西亚马主动脉破裂的发生率较高有关。
