Turc-Carel C, Dal Cin P, Boghosian L, Leong S P, Sandberg A A
Southwest Biomedical Research Institute, Scottsdale, AZ 85251.
Cancer Genet Cytogenet. 1988 Nov;36(1):131-5. doi: 10.1016/0165-4608(88)90083-0.
Chromosomal investigations in two unrelated lipoma samples are reported. The breakpoint involving 12q in chromosomal rearrangements could be assigned to band 12q13 in one case and 12q14 in the other case. Evidence is provided that cytogenetically distinct breakpoints on 12q may be found in lipoma cells, resolving previous disagreements based on interpretational difficulties.
报告了对两个无关脂肪瘤样本的染色体研究。在一个病例中,染色体重排中涉及12q的断点可定位于12q13带,在另一个病例中定位于12q14带。有证据表明,在脂肪瘤细胞中可能发现12q上细胞遗传学上不同的断点,解决了以往因解释困难而产生的分歧。