唾液酸在人脑肿瘤中的亚细胞定位

Subcellular localization of sialic acid in human brain tumors.

作者信息

Kökoğlu E, Sönmez H, Sarioğlu A C

机构信息

Department of Biochemistry, Cerrahpaşa Medical Faculty, Istanbul, Turkey.

出版信息

Cancer Lett. 1988 Dec 1;43(1-2):29-31. doi: 10.1016/0304-3835(88)90208-x.

DOI:10.1016/0304-3835(88)90208-x

PMID:3203327

Abstract

The subcellular localization of sialic acid has been investigated in various types of human brain tumors, such as astrocytoma, meningioma and primary malignant lymphoma. High levels of sialic acid were observed in the microsomal fraction of all types of tumors. However, there was no significant difference between values obtained in meningioma, primary malignant lymphoma, and normal tissue, in the fractions examining nucleus, mitochondria and supernatant.

摘要

已对多种类型的人脑肿瘤（如星形细胞瘤、脑膜瘤和原发性恶性淋巴瘤）中唾液酸的亚细胞定位进行了研究。在所有类型肿瘤的微粒体部分均观察到高水平的唾液酸。然而，在检查细胞核、线粒体和上清液的部分中，脑膜瘤、原发性恶性淋巴瘤和正常组织所获得的值之间没有显著差异。