Faculty of Medicine, Department of Social Medicine & Post-Graduate Program in Epidemiology, Federal University of Pelotas, Rua Marechal Deodoro, 1160, Pelotas CEP 96020-220, RS, Brazil.
Post-Graduate Program in Epidemiology, Federal University of Pelotas, Rua Marechal Deodoro, 1160, Pelotas CEP 96020-220, RS, Brazil.
Int J Environ Res Public Health. 2020 Feb 5;17(3):989. doi: 10.3390/ijerph17030989.
Medication use during pregnancy is a common practice that has been increasing in recent years. The aim of this study is to describe medication use among pregnant women from the 2015 Pelotas (Brazil) Birth Cohort Study. This paper relies on a population-based cohort study including 4270 women. Participants completed a questionnaire about the antenatal period, including information about medication use. We performed descriptive analyses of the sample and the medications used and adjusted analyses for the use of medications and self-medication. The prevalence of medication use was 92.5% (95% CI 91.7-93.3), excluding iron salts, folic acid, vitamins, and other minerals. The prevalence of self-medication was 27.7% (95% CI 26.3-29.1). In the adjusted analysis, women who had three or more health problems during pregnancy demonstrated higher use of medicines. Self-medication was higher in lower income groups and among smokers and multiparous women (three pregnancies or more). Acetaminophen, scopolamine, and dimenhydrinate were the medications most commonly used. This study describes the pattern of drug use among pregnant women in a population-based cohort study, with a high prevalence of self-medication. Greater awareness of the risks of self-medication during pregnancy is required, focusing on groups more prone to this practice, as well as ensuring qualified multidisciplinary prenatal care.
孕期用药是一种常见做法，近年来呈上升趋势。本研究旨在描述 2015 年佩洛塔斯（巴西）出生队列研究中孕妇的用药情况。本论文基于一项基于人群的队列研究，共纳入 4270 名女性。参与者完成了一份关于产前时期的问卷，其中包括用药信息。我们对样本和使用的药物进行了描述性分析，并对用药和自我用药进行了调整分析。用药的患病率为 92.5%（95%CI91.7-93.3），不包括铁盐、叶酸、维生素和其他矿物质。自我用药的患病率为 27.7%（95%CI26.3-29.1）。在调整分析中，孕期有 3 种或以上健康问题的女性显示出更高的用药率。收入较低的群体、吸烟者和多产妇（怀孕 3 次或以上）的自我用药率更高。对乙酰氨基酚、东莨菪碱和茶苯海明是最常用的药物。本研究在一项基于人群的队列研究中描述了孕妇的用药模式，自我用药率较高。需要提高对孕期自我用药风险的认识，重点关注更倾向于这种做法的群体，并确保合格的多学科产前保健。
