Department of Public Health and Pediatric Sciences, University of Turin, Medical School, Turin, Italy.
Department of Pediatrics, Azienda Ospedaliera Universitaria Città della Salute e della Scienza di Torino, Turin, Italy.
Microbes Infect. 2020 Sep;22(8):366-370. doi: 10.1016/j.micinf.2020.01.006. Epub 2020 Feb 6.
The human endogenous retroviruses (HERVs) are endogenous retroviruses that are inserted into the germ cell DNA of humans over 30 million years ago. Using real-time RT-PCR we describe HERV modulation by commensal microbes in the human gut. Infants, exclusively or predominant breast milk feeding, less than 12 weeks of age, during bacteria gut colonization, were assessed for eligibility. Our data demonstrate that the colonization with commensal microbes, in particular, Bifidobacterium spp., of the gut causes modulation of HERVs.
人类内源性逆转录病毒（HERV）是在 3000 多万年前插入人类生殖细胞 DNA 的内源性逆转录病毒。我们使用实时 RT-PCR 描述了肠道共生微生物对 HERV 的调节。对年龄小于 12 周、完全或主要母乳喂养、正在经历细菌肠道定植的婴儿进行了资格评估。我们的数据表明，肠道共生微生物（特别是双歧杆菌属）的定植会导致 HERV 的调节。
