Wuhan Children's Hospital (Wuhan Maternal and Child Healthcare Hospital), Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China; The State Key Laboratory Breeding Base of Basic Science of Stomatology and Key Laboratory for Oral Biomedicine of Ministry of Education, Department of Pediatric Dentistry, School and Hospital of Stomatology, Wuhan University, Wuhan, China.
Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
J Endod. 2020 Mar;46(3):352-357. doi: 10.1016/j.joen.2019.12.010. Epub 2020 Feb 5.
Calcium hydroxide has been used as a traditional pulpotomy agent for a long time but has some disadvantages. iRoot BP Plus (Innovative Bioceramix Inc, Vancouver, Canada) is a newly developed, ready-to-use calcium silicate-based bioactive ceramic with excellent bioactivity and sealing ability. However, whether iRoot BP Plus shows superiority over calcium hydroxide as a pulpotomy material on permanent incisors with complicated crown fractures remains unknown.
This research included 205 permanent incisors with complicated crown fractures. These teeth were treated with pulpotomy and divided into 2 groups according to the pulpotomy material (105 treated with iRoot BP Plus and 100 with calcium hydroxide). Clinical and radiographic information was collected during the 12- to 24-month follow-up period. The formation of reparative dentin bridges and pulp canal obliteration were analyzed using radiographs in both groups.
The success rates for recall in the average follow-up period of 17.5 ± 4.4 months (12-24 months) after pulpotomy treatment were significantly different between the 2 groups, with 99% for the iRoot BP Plus group and 93% for the calcium hydroxide group. Reparative dentin bridges were observed in 92.4% of the iRoot BP Plus group and 90% of the calcium hydroxide group, but the difference was not significant. Pulp canal obliteration was observed in 2 teeth (2%) in each group.
The success rates obtained in our study indicate that iRoot BP Plus as a pulpotomy agent can be a suitable alternative to calcium hydroxide to manage complicated crown fractures.
氢氧化钙作为牙髓切断术的传统药物已应用多年，但存在一些缺点。iRoot BP Plus（Innovative Bioceramix Inc，加拿大温哥华）是一种新开发的、即用型硅酸钙基生物活性陶瓷，具有优异的生物活性和密封能力。然而，iRoot BP Plus 作为牙髓切断剂应用于伴有复杂冠折的恒牙是否优于氢氧化钙，目前尚不清楚。
本研究纳入 205 颗伴有复杂冠折的恒牙。这些牙齿接受牙髓切断术治疗，并根据牙髓切断材料分为 2 组（105 颗用 iRoot BP Plus，100 颗用氢氧化钙）。在 12 至 24 个月的随访期间收集临床和影像学信息。分析两组的放射影像学资料，观察修复性牙本质桥的形成和牙髓腔闭锁情况。
平均随访 17.5±4.4 个月（12-24 个月）后，牙髓切断术治疗后的复诊成功率在两组间差异有统计学意义，iRoot BP Plus 组为 99%，氢氧化钙组为 93%。iRoot BP Plus 组有 92.4%的牙齿观察到修复性牙本质桥，氢氧化钙组有 90%的牙齿观察到修复性牙本质桥，但差异无统计学意义。两组各有 2 颗牙（2%）观察到牙髓腔闭锁。
本研究的成功率表明，iRoot BP Plus 作为牙髓切断剂，可替代氢氧化钙用于处理复杂冠折。
