继发于骨肉瘤的自发性气胸的发病机制。

Pathogenesis of Secondary Spontaneous Pneumothorax Complicating Osteosarcoma.

机构信息

Department of Thoracic Surgical Oncology, The Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan.

Division of Pathology, The Cancer Institute, Japanese Foundation for Cancer Research, Tokyo, Japan.

出版信息

Ann Thorac Surg. 2020 Aug;110(2):e81-e83. doi: 10.1016/j.athoracsur.2019.12.050. Epub 2020 Feb 7.

DOI:10.1016/j.athoracsur.2019.12.050

PMID:32035917

Abstract

This report describes a rare case of osteosarcoma of the right distal femur and secondary spontaneous pneumothorax in a 13-year-old girl. Secondary spontaneous pneumothorax complicating metastatic osteosarcoma is a rare but well-known phenomenon, with several suggested hypotheses for its pathogenesis. However, these hypotheses have not been confirmed. In the present case, the pathogenesis of secondary spontaneous pneumothorax complicating metastatic osteosarcoma was determined grossly, radiologically, and histopathologically. These findings may help to clarify further the pathogenesis of secondary spontaneous pneumothorax complicating metastatic osteosarcoma.

摘要

本报告描述了一例罕见的 13 岁女孩右侧股骨远端骨肉瘤合并继发性自发性气胸。继发于转移性骨肉瘤的自发性气胸是一种罕见但众所周知的现象，其发病机制有几种假说，但尚未得到证实。在本病例中，通过大体、影像学和组织病理学检查确定了继发于转移性骨肉瘤的自发性气胸的发病机制。这些发现可能有助于进一步阐明继发于转移性骨肉瘤的自发性气胸的发病机制。