Schott Harold C, Esser Melissa M
Department of Large Animal Clinical Sciences, Veterinary Medical Center, College of Veterinary Medicine, Michigan State University, Room D-202, 736 Wilson Road, East Lansing, MI 48824, USA.
Department of Large Animal Clinical Sciences, Veterinary Medical Center, College of Veterinary Medicine, Michigan State University, Room D-202, 736 Wilson Road, East Lansing, MI 48824, USA.
Vet Clin North Am Equine Pract. 2020 Apr;36(1):121-134. doi: 10.1016/j.cveq.2019.12.003. Epub 2020 Feb 6.
Clinicopathologic evaluation of renal function and renal disease in sick adult horses remains grounded in detection of azotemia, assessment of serum and urine electrolyte concentrations, and evaluation of urinalysis findings, including specific gravity, reagent strip analysis, and sediment examination. Because increases in serum or plasma urea nitrogen and creatinine concentrations are insensitive indicators of a decreased glomerular filtration rate, there is considerable interest in identifying novel biomarkers of renal function or injury in blood and urine, with serum symmetric dimethylarginine concentration being the most recent addition to the commercial market.
患病成年马的肾功能和肾脏疾病的临床病理评估仍基于氮质血症的检测、血清和尿液电解质浓度的评估以及尿液分析结果的评估，包括比重、试条分析和沉渣检查。由于血清或血浆尿素氮和肌酐浓度的升高是肾小球滤过率降低的不敏感指标，因此人们对鉴定血液和尿液中肾功能或损伤的新型生物标志物有很大兴趣，血清对称二甲基精氨酸浓度是商业市场上最新增加的指标。
