King J C, Corfield G S, Mouatt J G, Kan C Y, Moses P A
Veterinary Specialist Services - Small Animal Surgery Department, Gold Coast, Queensland, Australia.
Aust Vet J. 2020 Apr;98(4):156-163. doi: 10.1111/avj.12910. Epub 2020 Feb 9.
To assess the short- and long-term outcome of an anchored intervertebral titanium device (C-LOX) for the treatment of 10 dogs with disc-associated cervical spondylomyelopathy (DACSM) and 1 dog with osseous-associated cervical spondylomyelopathy.
Retrospective case series.
Dogs were included if they were diagnosed with either DACSM or osseous-associated cervical spondylomyelopathy via myelography with or without advanced imaging and underwent surgical distraction and stabilisation of the affected intervertebral disc with a C-LOX implant. Assessment included short-term neurological outcome, radiography immediately and 6 weeks' postsurgery, owner questionnaire and veterinary clinical assessment.
The mean follow-up time was 12 months. Improvement in neurological status was noted in 10 of 11 dogs. Screw loosening or subsidence occurred in five dogs. Revision surgery was performed in two dogs due to implant fracture (n = 1) and recurrence of spinal cord compression due to endplate subsidence around the implant (n = 1). Adjacent segment disease occurred in three dogs (30%) with DACSM at a mean of 11 months postsurgery.
The use of the C-LOX implant for dogs with cervical spondylomyelopathy resulted in a high rate of initial neurological improvement; however, there is a moderate incidence of minor and major complications that is comparable to previously described distraction-stabilisation techniques.
评估一种锚定椎间钛装置（C-LOX）治疗10只患有椎间盘相关性颈椎病脊髓病（DACSM）的犬和1只患有骨相关性颈椎病脊髓病的犬的短期和长期疗效。
回顾性病例系列研究。
通过脊髓造影（无论有无高级成像）诊断为DACSM或骨相关性颈椎病脊髓病，并接受手术撑开和使用C-LOX植入物稳定受影响椎间盘的犬被纳入研究。评估包括短期神经学结果、术后即刻和术后6周的X线摄影、主人问卷调查以及兽医临床评估。
平均随访时间为12个月。11只犬中有10只神经状态有所改善。5只犬出现螺钉松动或下沉。2只犬因植入物骨折（n = 1）和植入物周围终板下沉导致脊髓压迫复发（n = 1）而接受了翻修手术。3只患有DACSM的犬（30%）在术后平均11个月出现相邻节段疾病。
将C-LOX植入物用于患有颈椎病脊髓病的犬，可使初始神经学改善率较高；然而，与先前描述的撑开稳定技术相比，轻微和严重并发症的发生率中等。
