副作用对精神分裂症和双相情感障碍患者遵医嘱进行医学治疗的影响。
The impact of side effects on schizophrenia and bipolar disorder patients' adherence to prescribed medical therapy.
机构信息
Faculty of Nursing, Sağlık Bilimleri University, Istanbul, Turkey.
Department of Psychiatric Nursing, Faculty of Health Sciences, Giresun University, Giresun, Turkey.
出版信息
Perspect Psychiatr Care. 2020 Jul;56(3):691-696. doi: 10.1111/ppc.12483. Epub 2020 Feb 9.
PURPOSE
Our study aims to investigate how antipsychotic drugs' side effects impact schizophrenia and bipolar disorder patients and how this affects their adherence to prescribed medical therapy.
DESIGN AND METHODS
The study sample consists of 47 bipolar disorder and 45 schizophrenic patients. Data were collected using the Medication Adherence Rating Scale (MARS) and Liverpool University Neuroleptic Side Effect Rating Scale (LUNSERS).
FINDINGS
The mean total LUNSERS scores showed that bipolar disorder patients had more significant side effects compared with schizophrenic patients (P < .05). There was a moderate negative correlation between the mean MARS scores and mean LUNSERS scores of bipolar disorder patients (P < .05).
PRACTICE IMPLICATIONS
Nursing care actions and strategies should be planned and implemented to promote adherence to treatment.
目的
本研究旨在探讨抗精神病药物的副作用如何影响精神分裂症和双相情感障碍患者，并探讨这如何影响他们对规定医疗治疗的依从性。
设计和方法
研究样本包括 47 例双相情感障碍和 45 例精神分裂症患者。使用药物依从性评定量表（MARS）和利物浦大学神经阻滞剂副作用评定量表（LUNSERS）收集数据。
结果
LUNSERS 总分均值显示，双相情感障碍患者的副作用比精神分裂症患者更明显（P<0.05）。双相情感障碍患者的 MARS 评分均值与 LUNSERS 评分均值之间存在中度负相关（P<0.05）。
实践意义
应计划和实施护理措施和策略，以促进治疗依从性。
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